IL-25 and IL-33-responsive oligoclonal Th2 cells characterize nasal polyps with Th17 as the default signature in healthy nasal mucosa

被引：0
|
作者：
Lam, E. P. S. [1 ,2 ,3 ]
Kariyawasam, H. H. [2 ,3 ,4 ]
Rana, B. M. J. [2 ,3 ,5 ]
Durham, S. R. [2 ,3 ,6 ]
Mckenzie, A. N. J. [5 ]
Powell, N. [7 ,8 ]
Rimmer, J. [4 ]
Lund, V. J. [4 ]
Cousins, D. J. [2 ,3 ,9 ]
Till, S. J. [1 ,2 ,3 ]
机构：
[1] Kings Coll London, Div Asthma Allergy & Lung Biol, London WC2R 2LS, England
[2] MRC, London, England
[3] Asthma UK Ctr Allerg Mech Asthma, London, England
[4] UCL, Royal Natl Throat Nose Ear Hosp, Allergy & Med Rhinol Sect, London, England
[5] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
[6] Univ London Imperial Coll Sci Technol & Med, Sect Allergy & Clin Immunol, London, England
[7] Kings Coll London, Sect Allergy & Clin Immunol, London WC2R 2LS, England
[8] Kings Coll London, Div Transplantat Immunol & Mucosal Biol, London WC2R 2LS, England
[9] Univ Leicester, Dept Infect Immun & Inflammat, Leicester, Leics, England
来源：
ALLERGY | 2015年 / 70卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
214
引用
收藏
页码：105 / 105
页数：1
相关论文
共 50 条
  • [21] New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
    Hurst, SD
    Muchamuel, T
    Gorman, DM
    Gilbert, JM
    Clifford, T
    Kwan, S
    Menon, S
    Seymour, B
    Jackson, C
    Kung, TT
    Brieland, JK
    Zurawski, SM
    Chapman, RW
    Zurawski, G
    Coffman, RL
    JOURNAL OF IMMUNOLOGY, 2002, 169 (01): : 443 - 453
  • [22] Changing Characteristics of Treg/Th17 Cells in the Nasal Mucosa of a Mouse Model of Allergic Rhinitis and the Effect of Intervention with Anti-IL-17 Antibody
    Sun, Haiyong
    Liu, Baoxu
    Ma, Wei
    Ji, Dejun
    Guan, Bing
    DISCOVERY MEDICINE, 2024, 36 (185) : 1260 - 1267
  • [23] TSLP, IL-25 and IL-33 work in cooperation to drive TH2 and TH1 CD4+ T-Cell responses
    Comeau, Michael R.
    Martin, Tod J.
    Jessup, Heidi K.
    CYTOKINE, 2010, 52 (1-2) : 77 - 77
  • [24] IL-25 mediated Th2-biased inflammation in nasal polyps: role of respiratory virus infection and its modulation by interferon-alpha
    Haiyu, H.
    Yan, Y.
    Tan, K. S.
    Ong, H. H.
    Peng, Y.
    Oo, Y.
    Chow, V. T.
    Wang, D.
    ALLERGY, 2019, 74 : 54 - 54
  • [25] IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases
    Vocca, Lavinia
    Di Sano, Caterina
    Uasuf, Carina G.
    Sala, Angelo
    Riccobono, Oredana
    Gangemi, Sebastiano
    Albano, Giusy Daniela
    Bonanno, Anna
    Gagliardo, Rosalia
    Profita, Mirella
    IMMUNOBIOLOGY, 2015, 220 (08) : 954 - 963
  • [26] House Dust Mite Induces Bone Marrow IL-33-Responsive ILC2s and TH Cells
    Boberg, Emma
    Johansson, Kristina
    Malmhall, Carina
    Weidner, Julie
    Radinger, Madeleine
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (11)
  • [27] IL-25 enhances TH17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells
    Suto, Hajime
    Nambu, Aya
    Morita, Hideaki
    Yamaguchi, Sachiko
    Numata, Takafumi
    Yoshizaki, Takamichi
    Shimura, Eri
    Arae, Ken
    Asada, Yousuke
    Motomura, Kenichiro
    Kaneko, Mari
    Abe, Takaya
    Matsuda, Akira
    Iwakura, Yoichiro
    Okumura, Ko
    Saito, Hirohisa
    Matsumoto, Kenji
    Sudo, Katsuko
    Nakae, Susumu
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 142 (05) : 1500 - +
  • [28] IL-1 Family Cytokines Drive Th2 and Th17 Cells to Innocuous Airborne Antigens
    Kobayashi, Takao
    Iijima, Koji
    Checkel, James L.
    Kita, Hirohito
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2013, 49 (06) : 989 - 998
  • [29] IL-33 administration promotes both Th2 and Th17 responses and improves resolution during influenza infection
    Wissinger, Erika
    Vekaria, Seema
    Edwards, Lorna
    Lyonga, Daphne
    Godlee, Alexandra
    Lloyd, Clare
    Liew, Foo
    Hussell, Tracy
    JOURNAL OF IMMUNOLOGY, 2010, 184
  • [30] Decidual Interleukin-22-Producing CD4+T Cells (Th17/Th0/IL-22+and Th17/Th2/IL-22+, Th2/IL-22+, Th0/IL-22+), Which Also Produce IL-4, Are Involved in the Success of Pregnancy
    Logiodice, Federica
    Lombardelli, Letizia
    Kullolli, Ornela
    Haller, Herman
    Maggi, Enrico
    Rukavina, Daniel
    Piccinni, Marie-Pierre
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (02):
12345