Human Pulmonary Hyperpolarized 129Xe MRI: a Preliminary Study

被引：0
|
作者：
Yang, Hao [1 ]
Wang, Ke [1 ]
Zhang, Hui-Ting [2 ]
Xie, Jun-Shuai [2 ]
Wu, Guang-Yao [1 ]
Zhou, Xin [2 ]
机构：
[1] Wuhan Univ, Zhongnan Hosp, Dept Radiol, Wuhan 430071, Hubei, Peoples R China
[2] Chinese Acad Sci, Wuhan Inst Phys & Math, Natl Ctr Magnet Resonance Wuhan, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Hubei, Peoples R China
来源：
CHINESE PHYSICS LETTERS | 2018年 / 35卷 / 05期
基金：
中国国家自然科学基金;
关键词：
COMPUTED-TOMOGRAPHY; MAGNETIC-RESONANCE; HEALTHY-VOLUNTEERS; DISEASE; LUNG; COPD; SMOKERS; ASTHMA; HE-3;
D O I：
10.1088/0256-307X/35/5/058701
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We study the feasibility and safety of human lung hyperpolarized (HP) (129) Xe magnetic resonance imaging (MRI). There is no significant change in physiological parameters before and after the examinations of all subjects. Compared with computed tomography, HP (129) Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP Xe-129 MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP Xe-129 MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.
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页数：4
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