Highly diastereoselective synthesis of N-tert-butylsulfinylpropargylamines through direct addition of Alkynes to N-tert-butanesulfinimines

被引：47
|
作者：
Ding, Chang-Hua
Chen, Dong-Dong
Luo, Zhi-Bin
Dai, Li-Xin
Hou, Xue-Long
机构：
[1] State Key Lab Organomet Chem, Shanghai 200032, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai 200032, Peoples R China
来源：
SYNLETT | 2006年 / 08期
关键词：
imine; alkynylation; N-tert-butylsulfinylpropargylamine; diastereoselectivity;
D O I：
10.1055/s-2006-939076
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct addition of a variety of alkynes to N-tert-butane-sulfinyl aldimines in the presence of a suitable base provided the corresponding N-tert-butylsulfinylpropargylamines in high yields and high diastereoselectivity.
引用
收藏
页码：1272 / 1274
页数：3
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