Highly diastereoselective addition of alkoxyethynyl aluminium reagents to N-tert-butylsulfinyl aldimines

被引：12
|
作者：
Verrier, Charlie [1 ]
Carret, Sebastien [1 ]
Poisson, Jean-Francois [1 ]
机构：
[1] Univ Grenoble 1, Dept Chim Mol SERCO, UMR CNRS 5250, ICMG FR 2607, F-38041 Grenoble 9, France
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 12期
关键词：
REGIOSELECTIVE CLEAVAGE; ASYMMETRIC ADDITION; ALKYNYLATION; EPOXIDES; ALCOHOLS;
D O I：
10.1039/c3ob42352b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The addition of dimethylaluminium alkoxyacetylides to Ellman's sulfinylimines is described. The reaction proceeds with excellent diastereoselectivity and high yield to produce oxygenated propargylamines in one step starting from simple dichloroenol ethers.
引用
收藏
页码：1875 / 1878
页数：4
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