Development of ion-association methods for the spectrophotometric assay of trazodone

被引：0

作者：

Prasad, AVSS ^{[1
]}

Sastry, CSP ^{[1
]}

机构：

[1] Andhra Univ, Sch Chem, Foods & Drugs Labs, Visakhapatnam 530003, Andhra Pradesh, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2002年 / 79卷 / 05期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simple and sensitive spectrophotometric methods (M-1-M-3) for the assay of trazodone (TZ) are proposed. These methods are based on the formation of ion-association complex involving tertiary nitrogen of TZ and the acidic dye, supracene violet 3B (SV 3B) (M-1), tropaeolin 000 (TP 000) (M-2) or wool fast blue BL (WFB BL) (M-3). Beer's law and precision and accuracy of the methods are checked. The methods are suitable for the assay of trazodone in pharmaceutical formulations, and the recovery range is 99.17-99.16%.

引用

页码：452 / 454

页数：3

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