Subjective memory complaints and cognitive impairment in older people

被引:482
|
作者
Reid, Louise M. [1 ]
MacLullich, Alasdair M. J. [1 ]
机构
[1] Univ Edinburgh, Ctr Study Ageing Brain, Queens Med Res Inst, Edinburgh EH16 4TJ, Midlothian, Scotland
基金
英国医学研究理事会;
关键词
subjective memory complaints; mild cognitive impairment; dementia; cholinesterase inhibitors; cognition;
D O I
10.1159/000096295
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Subjective memory complaints (SMCs) are common in older people and are often thought to indicate cognitive impairment. We reviewed research on the relationship between SMCs and ( a) current cognitive function, (b) risk of future cognitive decline, and ( c) depression and personality. SMCs were found to be inconsistently related to current cognitive impairment but were more strongly related to risk of future cognitive decline. However, SMCs were consistently related to depression and some personality traits, e.g. neuroticism. In conclusion, the determinants of SMCs are complex. The utility of SMCs in the diagnosis of pre-dementia states (e.g. mild cognitive impairment) is uncertain and requires further evaluation. Copyright (C) 2006 S. Karger AG, Basel.
引用
收藏
页码:471 / 485
页数:15
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