Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

被引：45
|
作者：
de Paz, Jose L.
Spillmann, Dorothe
Seeberger, Peter H.
机构：
[1] ETH, Swiss Fed Inst Technol, Organ Chem Lab, CH-8093 Zurich, Switzerland
[2] Uppsala Univ, Dept Med Biochem & Microbiol, SE-75123 Uppsala, Sweden
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 29期
关键词：
D O I：
10.1039/b605318a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate - protein interactions.
引用
收藏
页码：3116 / 3118
页数：3
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