Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan

被引:21
|
作者
Hiramatsu, Yukihiro [1 ]
Miyaji, Yusuke [1 ,2 ]
Otsuka, Nao [1 ]
Arakawa, Yoshichika [3 ]
Shibayama, Keigo [1 ]
Kamachi, Kazunari [1 ]
机构
[1] Natl Inst Infect Dis, Tokyo, Japan
[2] St Marianna Univ, Sch Med, Kawasaki, Kanagawa, Japan
[3] Nagoya Univ, Grad Sch Med, Nagoya, Aichi, Japan
关键词
EUROPEAN COUNTRIES; UNITED-STATES; FITNESS; STRAINS; VACCINE;
D O I
10.3201/eid2304.161575
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014-2016 (8%) was significantly lower than the frequency in 2005-2007 (41%), 2008-2010 (35%), and 2011-2013 (25%). This reduction was closely associated with changes in genotypes.
引用
收藏
页码:699 / 701
页数:3
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