Palladium-catalyzed intermolecular Heck reaction of alkyl halides

被引：103

作者：

Zou, Yinjun ^{[1
]}

Zhou, Jianrong ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 28期

基金：

新加坡国家研究基金会;

关键词：

ORGANIC HALIDES; RADICAL ALKENYLATION; COUPLING REACTIONS; SIMPLE ALKENES; BROMIDES; BENZYL; ARYL; OLEFINATION; CYCLIZATION; SECONDARY;

D O I：

10.1039/c4cc00297k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intermolecular Heck reaction of common alkyl halides, a long-standing problem in palladium catalysis, is realized with a simple Pd/dppf catalyst. Both primary and secondary alkyl halides are suitable for coupling with aromatic olefins. Single electron transfer from (dppf) Pd-degrees to alkyl halide initiated the catalytic cycle and gave alkyl radicals.

引用

页码：3725 / 3728

页数：4

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