Successful treatment of refractory autoimmune haemolytic anaemia in a post-unrelated bone marrow transplant paediatric patient with rituximab

被引：38

作者：

Hongeng, S

Tardtong, P

Worapongpaiboon, S

Ungkanont, A

Jootar, S

机构：

[1] Mahidol Univ, Ramathibodi Hosp, Fac Med, Dept Pediat, Bangkok 10400, Thailand

[2] Mahidol Univ, Ramathibodi Hosp, Dept Pathol, Bangkok 10400, Thailand

[3] Mahidol Univ, Ramathibodi Hosp, Fac Med, Dept Internal Med, Bangkok 10400, Thailand

来源：

BONE MARROW TRANSPLANTATION | 2002年 / 29卷 / 10期

关键词：

unrelated bone marrow transplantation; autoimmune haemolytic anaemia; rituximab;

D O I：

10.1038/sj.bmt.1703551

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Here, we report a case of paediatric beta-thalassaemia major patient who underwent unrelated T cell-non-depleted bone marrow transplantation and developed a complication of autoimmune haemolytic anaemia (AIHA) refractory to corticosteroid and intravenous immunoglobulin therapy. After this child received two doses (375 mg/m(2)/dose) of rituximab (anti-CD20 monoclonal antibody), his AIHA was resolved.

引用

页码：871 / 872

页数：2

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