Successful treatment of refractory autoimmune haemolytic anaemia in a post-unrelated bone marrow transplant paediatric patient with rituximab

被引:38
|
作者
Hongeng, S
Tardtong, P
Worapongpaiboon, S
Ungkanont, A
Jootar, S
机构
[1] Mahidol Univ, Ramathibodi Hosp, Fac Med, Dept Pediat, Bangkok 10400, Thailand
[2] Mahidol Univ, Ramathibodi Hosp, Dept Pathol, Bangkok 10400, Thailand
[3] Mahidol Univ, Ramathibodi Hosp, Fac Med, Dept Internal Med, Bangkok 10400, Thailand
关键词
unrelated bone marrow transplantation; autoimmune haemolytic anaemia; rituximab;
D O I
10.1038/sj.bmt.1703551
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Here, we report a case of paediatric beta-thalassaemia major patient who underwent unrelated T cell-non-depleted bone marrow transplantation and developed a complication of autoimmune haemolytic anaemia (AIHA) refractory to corticosteroid and intravenous immunoglobulin therapy. After this child received two doses (375 mg/m(2)/dose) of rituximab (anti-CD20 monoclonal antibody), his AIHA was resolved.
引用
收藏
页码:871 / 872
页数:2
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