Transition-metal- and oxidant-free directed anodic C-H sulfonylation of N,N-disubstituted anilines with sulfinates

被引：80

作者：

Wu, Yan-Chen ^{[1
]}

Jiang, Shuai-Shuai ^{[1
]}

Luo, Shu-Zheng ^{[1
]}

Song, Ren-Jie ^{[1
]}

Li, Jin-Heng ^{[1
,2
]}

机构：

[1] Nanchang Hangkong Univ, Key Lab Jiangxi Prov Persistent Pollutants Contro, Nanchang 330063, Jiangxi, Peoples R China

[2] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 61期

关键词：

QUINOLINE N-OXIDES; SULFUR-DIOXIDE; C(SP(2))-H BONDS; BASE-FREE; SODIUM; ARYL; FUNCTIONALIZATION; 3-COMPONENT; AROMATICS; EFFICIENT;

D O I：

10.1039/c9cc03789f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new, practical directed anodic C-H sulfonylation of N,N-disubstituted anilines with sodium sulfinates for producing o- or p-amino arylsulfones and diarylsulfones is described. Employing the anodic strategy, the reaction proceeds efficiently under mild (room temperature) and transition-metal- and chemical oxidant-free conditions, and enables the formation of C-S bonds via directed activation of ortho- or para-C-H bond to the amino group with broad substrate scope and excellent site selectivity.

引用

页码：8995 / 8998

页数：4

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