Visuospatial working memory deficits in adolescent onset schizophrenia

被引：12
|
作者：
Vance, A. [1 ]
Hall, N.
Bellgrove, M. A.
Casey, M.
Karsz, F.
Maruff, P.
机构：
[1] Univ Melbourne, Dept Paediat, Acad Child Psychiat Unit, Parkville, Vic 3052, Australia
[2] Royal Childrens Hosp, Parkville, Vic 3052, Australia
[3] Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia
[4] Cogstate Ltd, Melbourne, Vic 3001, Australia
[5] Univ Melbourne, Sch Behav Sci, Cognit Neurosci Lab, Parkville, Vic 3052, Australia
来源：
SCHIZOPHRENIA RESEARCH | 2006年 / 87卷 / 1-3期
关键词：
adolescent-onset schizophrenia; visuospatial working memory; strategy; span;
D O I：
10.1016/j.schres.2006.04.025
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
This study determines that visuospatial working memory (VSWM) deficits are evident in adolescent-onset schizophrenia, while the spatial strategy and spatial span components of VSWM are spared. These findings imply that frontal-striatal-parietal neural networks are dysfunctional in adolescent-onset schizophrenia, while mid-dorsolateral and ventrolateral PFC functions remain intact: the current conceptualisation of schizophrenia as a progressive neurodevelopmental disorder is consistent with these results. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：223 / 227
页数：5
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