Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada

被引:8
|
作者
Shafer, Leigh Anne [1 ,2 ]
Nesca, Marcello [2 ,3 ]
Balshaw, Robert [3 ]
机构
[1] Univ Manitoba, Dept Internal Med, Winnipeg, MB, Canada
[2] Univ Manitoba, Dept Community Hlth Sci, Winnipeg, MB, Canada
[3] Univ Manitoba, George & Fay Yee Ctr Healthcare Innovat, Winnipeg, MB, Canada
来源
PLOS ONE | 2021年 / 16卷 / 01期
关键词
D O I
10.1371/journal.pone.0244537
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objectives The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impact that social distancing relaxation may have on the pandemic. Methods We fit a mathematical model to empirically estimated numbers of people infected, recovered, and died from COVID-19 in Manitoba. We then explored the impact of social distancing relaxation on: (a) time until near elimination of COVID-19 (< one case per million), (b) time until peak prevalence, (c) proportion of the population infected within one year, (d) peak prevalence, and (e) deaths within one year. Results Assuming a closed population, near elimination of COVID-19 in Manitoba could have been achieved in 4-6 months (by July or August) if there were no relaxation of social distancing. Relaxing to 15% of pre-COVID effective contacts may extend the local epidemic for more than two years (median 2.1). Relaxation to 50% of pre-COVID effective contacts may result in a peak prevalence of 31-38% of the population, within 3-4 months of initial relaxation. Conclusion Slight relaxation of social distancing may immensely impact the pandemic duration and expected peak prevalence. Only holding the course with respect to social distancing may have resulted in near elimination before Fall of 2020; relaxing social distancing to 15% of pre-COVID-19 contacts will flatten the epidemic curve but greatly extend the duration of the pandemic.
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页数:15
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