2-Phenylthio-3,3,3-trifluoropropene, its sulfoxide and sulfone: Synthesis and reactivity in 1,3-dipolar cycloadditions.

被引：34
|
作者：
Plancquaert, MA [1 ]
Redon, M [1 ]
Janousek, Z [1 ]
Viehe, HG [1 ]
机构：
[1] UNIV CATHOLIQUE LOUVAIN,CHIM ORGAN LAB,B-1348 LOUVAIN,BELGIUM
来源：
TETRAHEDRON | 1996年 / 52卷 / 12期
关键词：
D O I：
10.1016/0040-4020(96)00082-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Derivatives of 3,3,3-trifluoropropene 1 : alpha-sulfide 2, sulfoxide 3, sulfone 4 and bromide 6 are useful trifluoromethylated synthons. On reaction with diazo compounds, these derivatives can afford trifluoromethyl substituted pyrazolines, pyrazoles, cyclopropanes or allylsulfones in fair to excellent yields. 1,3-Dipolar cycloaddition of trifluoropropene derivatives 2-4 with N-benzylazomethine ylide provides disubstituted 3-trifluoromethyl-pyrrolidines.
引用
收藏
页码：4383 / 4396
页数：14
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