Does hyperandrogenic statute in the polycystic ovary syndrome constitute an obstacle to the success of in vitro fertilization?

被引:5
|
作者
Gaddas, M. [1 ]
Chaouache, N. [1 ]
Ajina, M. [2 ]
Tabka, Z. [1 ]
Ajina, M. Zaouali [1 ]
机构
[1] Fac Med Ibn el Jazzar, Lab Physiol & Explorat Fonct, Ave Mohamed Karoui, Sousse 4000, Tunisia
[2] CHU Farhat Hached, Unite Med Reprod, Ave Ibn el Jazzar, Sousse 4000, Tunisia
关键词
Hyperandrogenism; IVF; Polycystic ovarian; syndrome; SYNDROME PCOS; ANDROGEN RECEPTORS; INSULIN-RESISTANCE; DOWN-REGULATION; WOMEN; TESTOSTERONE; CYCLES; CELL; STIMULATION; APOPTOSIS;
D O I
10.1016/j.jgyn.2016.08.007
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives. The aim of this study was to evaluate the impact of initial androgenic statute of women with polycystic ovary syndrome (SOPK) on the expected results of in vitro fertilization (FIV). Materials and methods. It is about an exploratory study carried out in 61 unfertile SOPK patients, having profited all from a cycle of FIV/ICSI (intracytoplasmic sperm injection). We have divided our population in two groups according to their hormonal androgenic statute: groups with hyperandrogenism and without hyperandrogenism. We proceeded to note the anthropometric and hormonal parameters as well as results of FIV for each of the two groups. Results. SOPK patients with hyperandrogenism are more obese than their counterparts. Also, they have more oocytes collected after ovarian induction. In addition, we did not reveal any significant differences between our two study groups concerning parameters defining FIV response. Conclusion. Our findings suggest that hyperandrogenism statute in SOPK infertile women does not seem to compromise the results of FIV. On the contrary, it would make it possible to optimize the chances to puncture more significant number of oocytes. (C) 2016 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:1091 / 1098
页数:8
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