Putting the squeeze on mechanotransduction

被引：5

作者：

Helmke, BP ^{[1
]}

Schwartz, MA

机构：

[1] Univ Virginia, Dept Biomed Engn, Charlottesville, VA 22908 USA

[2] Univ Virginia, Dept Microbiol, Charlottesville, VA 22908 USA

[3] Univ Virginia, Cardiovasc Res Ctr, Charlottesville, VA 22908 USA

来源：

DEVELOPMENTAL CELL | 2004年 / 6卷 / 06期

关键词：

D O I：

10.1016/j.devcel.2004.05.013

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Both mechanical and chemical stimuli guide tissue function. In a recent paper, Tschumperlin et al. proposed that pressure acting on airway epithelium elicits mechanotransduction not by directly altering biochemical signaling but by regulating extracellular fluid volume to modulate ligand-receptor interactions.

引用

页码：745 / 746

页数：2

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