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Epidemiology of Rotavirus Infection in Children from a Rural and Urban Area, in Maputo, Southern Mozambique, before Vaccine Introduction
被引:12
|作者:
de Deus, Nilsa
[1
,2
]
Joao, Eva
[2
,3
]
Cuamba, Assa
[4
]
Cassocera, Marta
[1
]
Luis, Leopoldina
[2
]
Acacio, Sozinho
[1
,2
]
Mandomando, Inacio
[1
,2
]
Augusto, Orvalho
[4
]
Page, Nicola
[5
]
机构:
[1] INS, Eduardo Mondlane Salvador Allende Ave 1008, Maputo, Mozambique
[2] CISM, POB 1929, Manhica, Mozambique
[3] Inst Hyg & Trop Med, POB 1349-008, Lisbon, Portugal
[4] Univ Eduardo Mondlane, Fac Med, POB 257, Maputo, Mozambique
[5] NICD, Ctr Enter Dis, POB 2131, Johannesburg, South Africa
关键词:
rotavirus;
children;
diarrhea;
hospitalization;
epidemiology;
Mozambique;
DIARRHEA;
STRAINS;
AGE;
D O I:
10.1093/tropej/fmx032
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
This study aimed to describe the epidemiology of rotavirus infections in Mozambique before vaccine introduction. Between February 2012 and September 2013, stool specimens, demographic and clinical data were collected from 384 children <5 years old hospitalized with acute diarrhea in Mavalane General Hospital and Manhica District Hospital, southern Mozambique. The samples were tested for rotavirus A using enzyme-linked immunosorbent assay. The overall prevalence of rotavirus infection was 42.4% [95% confidence interval (95CI): 37.4-47.6%], and was similar in Manhica (44.3%; 95CI: 36.2-52.7%) and Mavalane (41.3%; 95CI: 34.9-47.9%). The highest prevalence of rotavirus infection was observed in children between 6 and 11months old. It was also observed that 162 (43.7%) of the children were underweight (weight-for-age z-score < -2), of which 61 were infected by rotavirus.
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页码:141 / 145
页数:5
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