Pulmonary vascular remodeling in pulmonary hypertension

被引：212
|
作者：
Tuder, Rubin M. [1 ]
机构：
[1] Univ Colorado, Div Pulm Sci & Crit Care Med, Dept Med, Program Translat Lung Res,Sch Med, Anschutz Med Campus Res 2,Room 9001, Aurora, CO 80045 USA
来源：
CELL AND TISSUE RESEARCH | 2017年 / 367卷 / 03期
关键词：
Pulmonary hypertension; Pulmonary remodeling; Endothelial cells; Smooth muscle cells; Lung; PLEXIFORM LESIONS; INFLAMMATION; PATHOLOGY; HISTOPATHOLOGY; INTERLEUKIN-1; INVOLVEMENT; INHIBITION; MECHANISMS; HYPOXIA; VESSELS;
D O I：
10.1007/s00441-016-2539-y
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms that underlie the remodeling process.
引用
收藏
页码：643 / 649
页数：7
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