MMX™ mesalamine

被引：0
|
作者：
Baker, Danial E. [1 ]
机构：
[1] Washington State Univ, Coll Pharm, Spokane, WA 99210 USA
来源：
REVIEWS IN GASTROENTEROLOGICAL DISORDERS | 2006年 / 6卷 / 03期
关键词：
MMX (TM) mesalamine; ulcerative colitis; Crohn's disease;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Most current drug delivery systems in the treatment of ulcerative colitis and Crohn's disease release the active drug at the least effective location for treatment. The pharmaceutical industry has been developing different delivery systems for Multi-Matrix System(TM) (MMX) mesalamine for the treatment of Crohn's disease and ulcerative colitis. The new oral mesalamine formulation is a once-daily MMX tablet that delivers the mesalamine to the colon, making it most useful in the treatment of ulcerative colitis. The MMX coating matrix and coating system begin dissolution in the final portion of the ileum. This type of oral formulation may make MMX a preferred agent over other oral mesalamine and mesalamine-prodrug formulations that release the drug proximally in the gastrointestinal tract. Unlike previous formulations, it can be administered once daily for the treatment of ulcerative colitis.
引用
收藏
页码：146 / 152
页数：7
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