Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening

被引：1
|
作者：
Hunter, Zoe L. [1 ]
Leeson, Hannah C. [1 ]
Shaker, Mohammed R. [1 ]
Wolvetang, Ernst J. [1 ]
Vadlamudi, Lata [2 ,3 ]
机构：
[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol AIBN, Brisbane, Qld 4072, Australia
[2] Univ Queensland, UQ Ctr Clin Res, Brisbane, Qld 4029, Australia
[3] Royal Brisbane & Womens Hosp, Dept Neurol, Brisbane, Qld 4029, Australia
来源：
STEM CELL RESEARCH | 2022年 / 60卷
关键词：
D O I：
10.1016/j.scr.2022.102673
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
In this paper, we describe the generation and validation of human induced pluripotent stem cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs) from 6 epilepsy patients using a non-integrative Sendai virus vector. These human cellular models will enable patient-specific drug screening to improve outcomes for individuals with this disorder.
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页数：5
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