Intramolecular nitrile oxide cycloaddition (INOC) of substituted amido-oximes

被引:15
|
作者
Chiacchio, U [1 ]
Corsaro, A [1 ]
Librando, V [1 ]
Rescifina, A [1 ]
Romeo, R [1 ]
Romeo, G [1 ]
机构
[1] UNIV MESSINA,DIPARTIMENTO FARMACOCHIM,I-98168 MESSINA,ITALY
关键词
D O I
10.1016/0040-4020(96)00884-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Functionalized enantiomerically pure 3,4-dehydropyrrolidin-2-one and 1,2-dehydropyrrolizidin-3-one systems have been achieved by intramolecular nitrile oxide cycloaddition, starting from enamido-oximes, and by subsequent reduction of the obtained cycloadducts. Copyright (C) 1996 Published by Elsevier Science Ltd
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页码:14323 / 14334
页数:12
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