Six new cycloartane triterpene glycosides from Actaea asiatica

被引:6
|
作者
Fan, Yun-Shuang [1 ,2 ]
Yao, Zhi [3 ]
Zhang, Yan-Wen [1 ]
Duan, Hong-Quan [1 ]
机构
[1] Tianjin Med Univ, Sch Pharmaceut Sci, Basic Med Res Ctr Tianjin, Tianjin 300070, Peoples R China
[2] Tianjin Polytech Univ, Key Lab Hollow Fiber Membrane Mat & Membrane Proc, Minist Educ, Tianjin 300160, Peoples R China
[3] Tianjin Med Univ, Dept Immunol, Tianjin 300070, Peoples R China
关键词
Ranunculaceae; Actaea asiatica; cycloartane triterpene glycosides; cytotoxic activities; CIMICIFUGA-RACEMOSA; CONSTITUENTS;
D O I
10.1080/10286020902819848
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Six new cycloartane triterpene glycosides, (3',12 beta)-O-diacetyl-cimigenol-3-O-beta-D-xylopyranoside (1), (4',25)-O-diacetyl-cimigenol-3-O-beta-D-xylopyranoside (2), 2'-Oacetyl-25-O-methyl-cimigenol-3-O-beta-D-xylopyranoside (3), 2'-O-acetyl-25-O-ethyl-cimigenol-3-O-beta-D-xylopyranoside (4), 3'-O-acetyl-cimicifugoside (5), and 4'-Oacetyl-23-epi-26-deoxycimifugoside (6), were isolated from the rhizomes of Actaea asiatica. Their structures were elucidated on the basis of chemical methods and spectroscopic analysis. Compounds 1,2,4-6 exhibited positive cytotoxic activities.
引用
收藏
页码:588 / 596
页数:9
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