AN OVERVIEW OF THERAPEUTIC POTENTIAL OF THYMOQUINONE

被引:5
|
作者
Agarwal, Swati [1 ]
Srivastava, Rashmi [1 ]
Mishra, Neetu [2 ]
机构
[1] Univ Allahabad, Ctr Food Technol, Allahabad 211002, Uttar Pradesh, India
[2] Univ Allahabad, Dept Home Sci, Allahabad 211002, Uttar Pradesh, India
关键词
Thymoquinone; Nigella sativa; Therapeutic potential; Anti-oxidant; Anti-microbial; Anti-inflammatory; NIGELLA-SATIVA OIL; OXIDATIVE STRESS; CELLS; CONSTITUENT; ATHEROSCLEROSIS; 5-LIPOXYGENASE; OSTEOSARCOMA; ATTENUATION; APOPTOSIS; MOLECULE;
D O I
10.13040/IJPSR.0975-8232.10(8).3532-39
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Herbal medication has attracted much attention in recent years and is being used as an alternative to chemical medicines. Some evidence supports the positive effects of medicinal plants in the prevention and treatment of different types of diseases. Thymoquinone (TQ) is the most abundant component of Nigella sativa seeds, and most of the properties of Nigella sativa are attributed primarily to TQ. It belongs to a class of naturally presenting phenols, chemically known as 2-isopropyl-5-methyl benzo-1, 4-quinone (C10H12O2), is a dark yellow crystalline monoterpene diketone, abundantly found in the seeds of Nigella sativa. Besides Nigella sativa, TQ is an active ingredient of several plants as Juniperus, Monarda, Coridothymus, Agastache, Satureja. It has been reported to possess various beneficial therapeutic effects including anti-oxidant, anti-inflammatory, anti-microbial, anti-diabetic, hepato-protective and cardioprotective effects. It is significant to say that TQ may be effective as a powerful contender of natural origin with therapeutic potential against an array of maladies.
引用
收藏
页码:3532 / 3539
页数:8
相关论文
共 50 条
  • [1] Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer
    Banerjee, Sanjeev
    Padhye, Subhash
    Azmi, Asfar
    Wang, Zhiwei
    Philip, Philip A.
    Kucuk, Omer
    Sarkar, Fazlul H.
    Mohammad, Ramzi M.
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2010, 62 (07): : 938 - 946
  • [2] Potential therapeutic effects of thymoquinone on treatment of amphetamine abuse
    Nurul Farah Aina Md Fauzi
    Nor Hidayah Abu Bakar
    Nasir Mohamad
    Khairi Che Mat
    Syed Hadzrullathfi Syed Omar
    Mohd Shahril Othman
    Rohayah Husain
    Muhamad Zaid Ismail
    Asian Pacific Journal of Tropical Biomedicine, 2018, (03) : 187 - 188
  • [3] Potential therapeutic effects of thymoquinone on treatment of amphetamine abuse
    Fauzi, Nurul Farah Aina Md
    Abu Bakar, Nor Hidayah
    Mohamad, Nasir
    Mat, Khairi Che
    Omar, Syed Hadzrullathfi Syed
    Othman, Mohd Shahril
    Husain, Rohayah
    Ismail, Muhamad Zaid
    ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE, 2018, 8 (03) : 187 - 188
  • [4] Thymoquinone in autoimmune diseases: Therapeutic potential and molecular mechanisms
    Ali, Md Yousuf
    Akter, Zakia
    Mei, Zhiqiang
    Zheng, Meiling
    Tania, Mousumi
    Khan, Md Asaduzzaman
    BIOMEDICINE & PHARMACOTHERAPY, 2021, 134
  • [5] Thymoquinone: A small molecule from nature with high therapeutic potential
    Malik, Safiya
    Singh, Amardeep
    Negi, Poonam
    Kapoor, Vijay Kumar
    DRUG DISCOVERY TODAY, 2021, 26 (11) : 2716 - 2725
  • [6] Therapeutic potential of naringin: an overview
    Chen, Rui
    Qi, Qiao-Ling
    Wang, Meng-Ting
    Li, Qi-Yan
    PHARMACEUTICAL BIOLOGY, 2016, 54 (12) : 3203 - 3210
  • [7] Therapeutic potential of gossypol: An overview
    Keshmiri-Neghab, Hoda
    Goliaei, Bahram
    PHARMACEUTICAL BIOLOGY, 2014, 52 (01) : 124 - 128
  • [8] Therapeutic Potential of Thymoquinone and Its Nanoformulations in Pulmonary Injury: A Comprehensive Review
    Al-Gabri, Naif A.
    Saghir, Sultan A. M.
    Al-Hashedi, Sallah A.
    El-Far, Ali H.
    Khafaga, Asmaa F.
    Swelum, Ayman A.
    Al-wajeeh, Abdullah S.
    Mousa, Shaker A.
    Abd El-Hack, Mohamed E.
    Naiel, Mohammed A. E.
    El-Tarabily, Khaled
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2021, 16 : 5117 - 5131
  • [9] Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin
    Goyal, Sameer N.
    Prajapati, Chaitali P.
    Gore, Prashant R.
    Patil, Chandragouda R.
    Mahajan, Umesh B.
    Sharma, Charu
    Talla, Sandhya P.
    Ojha, Shreesh K.
    FRONTIERS IN PHARMACOLOGY, 2017, 8
  • [10] An Overview on Renoprotective Effects of Thymoquinone
    Shaterzadeh-Yazdi, Hanieh
    Noorbakhsh, Mohammad-Foad
    Samarghandian, Saeed
    Farkhondeh, Tahereh
    KIDNEY DISEASES, 2018, 4 (02) : 74 - 82