PBT2 in Huntington Disease: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial

被引:0
|
作者
机构
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
S451 WIP
引用
收藏
页码:S51 / S52
页数:2
相关论文
共 50 条
  • [1] Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial
    Angus, D.
    Herd, C.
    Stone, C.
    Stout, J.
    Wieler, M.
    Reilmann, R.
    Ritchie, C. W.
    Dorsey, E. R.
    Helles, K.
    Kayson, E.
    Oakes, D.
    Rosas, H. D.
    Vaughan, C.
    Panegyres, P. K.
    Ames, D.
    Goh, A.
    Agarwal, P.
    Churchyard, A.
    Murathodizic, M.
    Chua, P.
    Germaine, D.
    Lim, L.
    Mack, H.
    Loy, C.
    Griffith, J.
    Mitchell, P.
    Corey-Bloom, J.
    Gluhm, S.
    Goldstein, J.
    Levi, L.
    Margolis, R.
    Yoritomo, N.
    Janicki, S.
    Marder, K.
    Clouse, R.
    Singer, C.
    Moore, H.
    Padron, N.
    Kostyk, S.
    Daley, A.
    Segro, V.
    Kumar, R.
    Anderson, K.
    Drazinic, C.
    Hennig, B.
    Nance, M.
    Molho, E.
    Criswell, S.
    LeDoux, M. S.
    Guyot, S.
    LANCET NEUROLOGY, 2015, 14 (01): : 39 - 47
  • [2] Etanercept in Alzheimer disease: A randomized, placebo-controlled, double-blind, phase 2 trial
    Butchart, Joseph
    Brook, Laura
    Hopkins, Vivienne
    Teeling, Jessica
    Puentener, Ursula
    Culliford, David
    Sharples, Richard
    Sharif, Saif
    McFarlane, Brady
    Raybould, Rachel
    Thomas, Rhodri
    Passmore, Peter
    Perry, V. Hugh
    Holmes, Clive
    NEUROLOGY, 2015, 84 (21) : 2161 - 2168
  • [3] ETANERCEPT IN ALZHEIMER DISEASE: A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, PHASE 2 TRIAL
    Tufan, Ayse N.
    Tufan, Fatih
    NEUROLOGY, 2015, 85 (23) : 2083 - 2084
  • [4] A Randomized, Double-Blind, Placebo-Controlled Trial of Pridopidine in Huntington's Disease
    Kieburtz, Karl
    McGarry, Andrew
    McDermott, Michael
    Kayson, Elise
    Harrison, Madaline
    Marder, Karen
    Walker, Francis
    MOVEMENT DISORDERS, 2013, 28 (10) : 1407 - 1415
  • [5] A Randomized, Double-Blind, Placebo-Controlled Trial Evaluating Cysteamine in Huntington's Disease
    Verny, Christophe
    Bachoud-Levi, Anne-Catherine
    Durr, Alexandra
    Goizet, Cyril
    Azulay, Jean-Philippe
    Simonin, Clemence
    Tranchant, Christine
    Calvas, Fabienne
    Krystkowiak, Pierre
    Charles, Perrine
    Youssov, Katia
    Scherer, Clarisse
    Prundean, Adriana
    Olivier, Audrey
    Reynier, Pascal
    Saudou, Frederic
    Maison, Patrick
    Allain, Philippe
    von Studnitz, Erica
    Bonneau, Dominique
    MOVEMENT DISORDERS, 2017, 32 (06) : 932 - 936
  • [6] Ethyl-EPA in Huntington disease - A double-blind, randomized, placebo-controlled trial
    Puri, BK
    Leavitt, BR
    Hayden, MR
    Ross, CA
    Rosenblatt, A
    Greenamyre, JT
    Hersch, S
    Vaddadi, KS
    Sword, A
    Horrobin, DF
    Manku, M
    Murck, H
    NEUROLOGY, 2005, 65 (02) : 286 - 292
  • [7] Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease:: a phase IIa, double-blind, randomised, placebo-controlled trial
    Lannfelt, Lars
    Blennow, Kaj
    Zetterberg, Henrik
    Batsman, Stellan
    Ames, David
    Hrrison, John
    Masters, Colin L.
    Targum, Steve
    Bush, Ashley I.
    Murdoch, Ross
    Wilson, Janet
    Ritchie, Craig W.
    LANCET NEUROLOGY, 2008, 7 (09): : 779 - 786
  • [8] Completion of a Randomized Controlled Safety and Tolerability Trial of PBT2 in Huntington's Disease
    Dorsey, R.
    NEUROTHERAPEUTICS, 2014, 11 (01) : 225 - 225
  • [9] Doxycycline in Creutzfeldt-Jakob disease: A phase 2, randomized, double-blind, placebo-controlled trial
    Brandel, Jean-Philippe
    Marcon, Gabriella
    Coudert, Mathieu
    Tettamanti, Mauro
    Welaratne, Arlette
    Giacone, Georgio
    Azimi, Shohreh
    Pietrini, Vladimiro
    Fabreguettes, Jean-Roch
    Imperiale, Daniele
    Aucan, Christophe
    Lucca, Ugo
    Mallet, Alain
    Salmona, Mario
    Zerr, Inga
    Redaelli, Veronica
    Forloni, Gianluigi
    Haik, Stephane
    Tagliavini, Fabrizio
    PRION, 2013, 7 : 62 - 62
  • [10] A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease
    McGarry, Andrew
    McDermott, Michael
    Kieburtz, Karl
    de Blieck, Elisabeth A.
    Beal, Flint
    Marder, Karen
    Ross, Christopher
    Shoulson, Ira
    Gilbert, Peter
    Mallonee, William M.
    Guttman, Mark
    Wojcieszek, Joanne
    Kumar, Rajeev
    LeDoux, Mark S.
    Jenkins, Mary
    Rosas, H. Diana
    Nance, Martha
    Biglan, Kevin
    Como, Peter
    Dubinsky, Richard M.
    Shannon, Kathleen M.
    O'Suilleabhain, Padraig
    Chou, Kelvin
    Walker, Francis
    Martin, Wayne
    Wheelock, Vicki L.
    McCusker, Elizabeth
    Jankovic, Joseph
    Singer, Carlos
    Sanchez-Ramos, Juan
    Scott, Burton
    Suchowersky, Oksana
    Factor, Stewart A.
    Higgins, Donald S., Jr.
    Molho, Eric
    Revilla, Fredy
    Caviness, John N.
    Friedman, Joseph H.
    Perlmutter, Joel S.
    Feigin, Andrew
    Anderson, Karen
    Rodriguez, Ramon
    McFarland, Nikolaus R.
    Margolis, Russell L.
    Farbman, Eric S.
    Raymond, Lynn A.
    Suski, Valerie
    Kostyk, Sandra
    Colcher, Amy
    Seeberger, Lauren
    NEUROLOGY, 2017, 88 (02) : 152 - 159