Molecular Basis for Ca2+ Binding of RyR2 for Channel Activation and Diseases States

被引：1
|
作者：
Murayama, Takashi [1 ]
Ogawa, Haruo [2 ]
Kurebayashi, Nagomi [1 ]
Sakurai, Takashi [1 ]
机构：
[1] Juntedno Univ, Sch Med, Dept Pharmacol, Tokyo, Japan
[2] Univ Tokyo, Inst Mol & Cellular Biosci, Tokyo, Japan
来源：
BIOPHYSICAL JOURNAL | 2018年 / 114卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2017.11.3364
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
3085-Pos B
引用
收藏
页码：622A / 622A
页数：1
相关论文
共 50 条
  • [41] Targeting the RyR2 I-domain as a novel strategy to correct mutationlinked Ca2+ release channel dysfunction.
    Jundi, Hala
    Lai, F. Anthony
    George, Christopher H.
    BIOPHYSICAL JOURNAL, 2007, : 262A - 262A
  • [42] Developing new anti-arrhythmics:: Clues from the molecular basis of cardiac ryanodine receptor (RyR2) Ca2+-release channel dysfunction
    George, Christopher H.
    Lai, F. Anthony
    CURRENT PHARMACEUTICAL DESIGN, 2007, 13 (31) : 3195 - 3211
  • [43] Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation
    Sommese, Leandro M.
    Florencia Racioppi, Maria
    Shen, Xin
    Orlowski, Alejandro
    Valverde, Carlos A.
    Louch, William E.
    Vila Petroff, Martin
    Gonano, Luis A.
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2022, 474 (06): : 625 - 636
  • [44] Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation
    Leandro M. Sommese
    María Florencia Racioppi
    Xin Shen
    Alejandro Orlowski
    Carlos A. Valverde
    William E. Louch
    Martín Vila Petroff
    Luis A. Gonano
    Pflügers Archiv - European Journal of Physiology, 2022, 474 : 625 - 636
  • [45] Mg2+ activates the ryanodine receptor type 2 (RyR2) at intermediate Ca2+ concentrations
    Chugun, Akihito
    Sato, Osamu
    Takeshima, Hiroshi
    Ogawa, Yasuo
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2007, 292 (01): : C535 - C544
  • [46] Different Ca2+ dependence of RyR2 activity in ventricular and atrial muscles from swine
    Chugun, A
    Kurebayashi, N
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2005, 39 (06) : 1009 - 1010
  • [47] Attempts to Create Transgenic Mice Carrying the Q3924E Mutation in RyR2 Ca2+ Binding Site
    Zhang, Xiao-hua
    Tang, Fu-lei
    Trouten, Allison M.
    Morad, Martin
    CELLS, 2024, 13 (24)
  • [48] FRET Detection of Calmodulin Binding to the Cardiac RyR2 Calcium Release Channel
    Guo, Tao
    Fruen, Bradley R.
    Nitu, Florentin R.
    Nguyen, Trinh D.
    Yang, Yi
    Cornea, Razvan L.
    Bers, Donald M.
    BIOPHYSICAL JOURNAL, 2011, 101 (09) : 2170 - 2177
  • [49] Ca2+-calmodulin Increases RyR2 Open Probability Yet Reduces Ryanoid Association With RyR2
    Sigalas, Charalambos
    Bayo-Martin, Belen
    Jane, David
    Sitsapesan, Rebecca
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 110A - 110A
  • [50] RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation , and Npas4/RyR2 expression
    Lobos, Pedro
    Cordova, Alex
    Vega-Vasquez, Ignacio
    Ramirez, Omar A.
    Adasme, Tatiana
    Toledo, Jorge
    Cerda, Mauricio
    Hartel, Steffen
    Paula-Lima, Andrea
    Hidalgo, Cecilia
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (33)
12345