The various aspects of the existing knowledge on the physiological role of melatonin and its mode of action in circadian rhythms and sleep are presented. Furthermore, the possibility of its clinical application in maintenance of sleep under regular and environmental changes is discussed.
机构:
Cornell Univ, New York Hosp Queens, Weill Med Coll, New York, NY 10021 USACornell Univ, New York Hosp Queens, Weill Med Coll, New York, NY 10021 USA
机构:
Tokyo Med Univ, Dept Psychiat, Tokyo 1600023, JapanTokyo Med Univ, Dept Somnol, Shinjuku Ku, Tokyo 1600023, Japan
Takaesu, Yoshikazu
Komada, Yoko
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机构:Tokyo Med Univ, Dept Somnol, Shinjuku Ku, Tokyo 1600023, Japan
Komada, Yoko
Inoue, Yuichi
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Tokyo Med Univ, Dept Somnol, Shinjuku Ku, Tokyo 1600023, Japan
Tokyo Med Univ, Dept Psychiat, Tokyo 1600023, JapanTokyo Med Univ, Dept Somnol, Shinjuku Ku, Tokyo 1600023, Japan