Melatonin for the treatment of disorders in circadian rhythm and sleep: Could it form a basis for medication?

被引:6
|
作者
Nir, I [1 ]
机构
[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Fac Med, Dept Pharmacol, IL-91120 Jerusalem, Israel
来源
RECEPTORS & CHANNELS | 2003年 / 9卷 / 06期
关键词
circadian rhythms; melatonin; sleep disorders;
D O I
10.3109/714041018
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The various aspects of the existing knowledge on the physiological role of melatonin and its mode of action in circadian rhythms and sleep are presented. Furthermore, the possibility of its clinical application in maintenance of sleep under regular and environmental changes is discussed.
引用
下载
收藏
页码:379 / 385
页数:7
相关论文
共 50 条
  • [1] Melatonin treatment for circadian rhythm sleep disorders
    Kamei, Y
    Hayakawa, T
    Urata, J
    Uchiyama, M
    Shibui, K
    Kim, K
    Kudo, Y
    Okawa, M
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2000, 54 (03) : 381 - 382
  • [2] Melatonin treatment for circadian rhythm sleep disorders
    Okawa, M
    Uchiyama, M
    Ozaki, S
    Shibui, K
    Kamei, Y
    Hayakawa, T
    Urata, J
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 1998, 52 (02) : 259 - 260
  • [3] Circadian rhythm sleep disorders in the blind and their treatment with melatonin
    Skene, Debra J.
    Arendt, Josephine
    SLEEP MEDICINE, 2007, 8 (06) : 651 - 655
  • [4] Use of melatonin for sleep and circadian rhythm disorders
    Sack, RL
    Lewy, AJ
    Hughes, RJ
    ANNALS OF MEDICINE, 1998, 30 (01) : 115 - 121
  • [5] Treatment of circadian rhythm disorders - Melatonin
    Arendt, J
    Deacon, S
    CHRONOBIOLOGY INTERNATIONAL, 1997, 14 (02) : 185 - 204
  • [6] The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders
    Pandi-Perumal, Seithikurippu R.
    Trakht, Ilya
    Spence, D. Warren
    Srinivasan, Venkataramanujan
    Dagan, Yaron
    Cardinali, Daniel P.
    NATURE CLINICAL PRACTICE NEUROLOGY, 2008, 4 (08): : 436 - 447
  • [7] The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders
    Seithikurippu R Pandi-Perumal
    Ilya Trakht
    D Warren Spence
    Venkataramanujan Srinivasan
    Yaron Dagan
    Daniel P Cardinali
    Nature Clinical Practice Neurology, 2008, 4 : 436 - 447
  • [8] Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders
    Hardeland, Ruediger
    CURRENT OPINION IN INVESTIGATIONAL DRUGS, 2009, 10 (07) : 691 - 701
  • [9] Shedding Light on the Effectiveness of Melatonin for Circadian Rhythm Sleep Disorders
    Zee, Phyllis C.
    SLEEP, 2010, 33 (12) : 1581 - 1582
  • [10] The role of the thalamus in sleep, pineal melatonin production, and circadian rhythm sleep disorders
    Jan, James E.
    Reiter, Russel J.
    Wasdell, Michael B.
    Bax, Martin
    JOURNAL OF PINEAL RESEARCH, 2009, 46 (01) : 1 - 7