Methadone is not a mechanism-based inhibitor of cytochrome P450 2D6

被引：0
|
作者：
Heydari, A [1 ]
Rostami-Hodjegan, A [1 ]
Rowland-Yeo, K [1 ]
Lennard, MS [1 ]
Tucker, GT [1 ]
机构：
[1] Univ Sheffield, Royal Hallamshire Hosp, Sheffield S10 2JF, S Yorkshire, England
来源：
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2004年 / 57卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：687 / 687
页数：1
相关论文
共 50 条
  • [41] Inhibitory monoclonal antibodies to human cytochrome P450 2D6
    Krausz, KW
    Yang, TJ
    Gonzalez, FJ
    Shou, MG
    Gelboin, HV
    BIOCHEMICAL PHARMACOLOGY, 1997, 54 (01) : 15 - 17
  • [42] Inhibition of human cytochrome P450 2D6 by schering 66712
    Butler, Brendan Francis
    Palamanda, Jairam
    Nomeir, Amin A.
    Guengerich, F. Peter
    Furge, Laura Lowe
    FASEB JOURNAL, 2007, 21 (05): : A670 - A670
  • [43] Tardive dyskinesia and cytochrome P450 2D6 genotyping in schizophrenia
    Lam, LCW
    Ungvari, GS
    Garcia, M
    Kwong, SL
    Chiu, HFK
    SCHIZOPHRENIA RESEARCH, 2000, 41 (01) : 261 - 261
  • [44] PERSONALIZED PHARMACOTHERAPY IN A PATIENT WITH CYTOCHROME P450 2D6 POLYMORPHISM
    Paul, Sheeba
    Lu, Celia
    Block, Lauren
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2017, 32 : S561 - S562
  • [45] Ligand-Based Site of Metabolism Prediction for Cytochrome P450 2D6
    Rydberg, Patrik
    Olsen, Lars
    ACS MEDICINAL CHEMISTRY LETTERS, 2012, 3 (01): : 69 - 73
  • [46] A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment
    Shiran, MR
    Chowdry, J
    Rostami-Hodjegan, A
    Ellis, SW
    Lennard, MS
    Iqbal, MZ
    Lagundoye, O
    Seivewright, N
    Tucker, GT
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 56 (02) : 220 - 224
  • [47] Structure-Based Site of Metabolism Prediction for Cytochrome P450 2D6
    Moors, Samuel L. C.
    Vos, Ann M.
    Cummings, Maxwell D.
    Van Vlijmen, Herman
    Ceulemans, Arnout
    JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (17) : 6098 - 6105
  • [48] Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos
    D'Agostino, Jaime
    Zhang, Haoming
    Kenaan, Cesar
    Hollenberg, Paul F.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2015, 28 (07) : 1484 - 1495
  • [49] Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4 and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
    Paludetto, Marie-Noeurolle
    Kurkela, Mika
    Kahma, Helina
    Backman, Janne T.
    Niemi, Mikko
    Filppula, Anne M.
    DRUG METABOLISM AND DISPOSITION, 2023, 51 (03) : 293 - 305
  • [50] Human liver cytochrome P450 2D6 genotype, full-length messenger ribonucleic acid, and activity assessed with a novel cytochrome P450 2D6 substrate
    McConnachie, L
    Bodor, M
    Kowdley, K
    Levy, A
    Tung, B
    Thummel, K
    Phillips, B
    Bajpai, M
    Chi, V
    Esmay, JD
    Shen, DA
    Ho, RJY
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (04) : 282 - 297
12345