Prostate cancer detection using multiparametric 3-tesla MRI and fusion biopsy: preliminary results

被引:5
|
作者
Mussi, Thais Caldara [1 ]
Garcia, Rodrigo Gobbo [2 ]
Gomes de Queiroz, Marcos Roberto [2 ]
Lemos, Gustavo Caserta [3 ]
Baroni, Ronaldo Hueb [1 ]
机构
[1] Hosp Israelita Albert Einstein, Dept Radiol & Diagnost Imagem, Av Albert Einstein 627, BR-05651901 Sao Paulo, SP, Brazil
[2] Hosp Israelita Albert Einstein, Dept Intervencao Guiada Imagem, Sao Paulo, SP, Brazil
[3] Hosp Israelita Albert Einstein, Dept Urol, Sao Paulo, SP, Brazil
来源
INTERNATIONAL BRAZ J UROL | 2016年 / 42卷 / 05期
关键词
Prostatic Neoplasms; Magnetic Resonance Imaging; Biopsy; Prostate; RESONANCE; ANTIGEN; LOCALIZATION;
D O I
10.1590/S1677-5538.IBJU.2015.0204
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objective: To evaluate the diagnostic efficacy of transrectal ultrasonography (US) biopsy with imaging fusion using multiparametric (mp) magnetic resonance imaging (MRI) in patients with suspicion of prostate cancer (PCa), with an emphasis on clinically significant tumors according to histological criteria. Materials and Methods: A total of 189 consecutive US/MRI fusion biopsies were performed obtaining systematic and guided samples of suspicious areas on mpMRI using a 3 Tesla magnet without endorectal coil. Clinical significance for prostate cancer was established based on Epstein criteria. Results: In our casuistic, the average Gleason score was 7 and the average PSA was 5.0ng/mL. Of the 189 patients that received US/MRI biopsies, 110 (58.2%) were positive for PCa. Of those cases, 88 (80%)were clinically significant, accounting for 46.6% of all patients. We divided the MRI findings into 5 Likert scales of probability of having clinically significant PCa. The positivity of US/MRI biopsy for clinically significant PCa was 0%, 17.6% 23.5%, 53.4% and 84.4% for Likert scores 1, 2, 3, 4 and 5, respectively. There was a statistically significant difference in terms of biopsy results between different levels of suspicion on mpMRI and also when biopsy results were divided into groups of clinically non-significant versus clinically significant between different levels of suspicion on mpMRI (p-value <0.05 in both analyzes). Conclusion: We found that there is a significant difference in cancer detection using US/MRI fusion biopsy between low-probability and intermediate/high probability Likert scores using mpMRI.
引用
收藏
页码:897 / 905
页数:9
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