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Guangdong Prov Acad Chinese Med Sci, Guangzhou Univ Chinese Med, Guangdong Prov Hosp Tradit Chinese Med, Dept Pathol, 111 Dade Rd, Guangzhou 510120, Guangdong, Peoples R China WuXi AppTec, Translat Biosci & Diagnost, 288 Fute Zhong Rd,Waigaoqiao Free Trade Zone, Shanghai 200131, Peoples R China