Histone H2AX Phosphorylation As a Measure of DNA Double Strand Breaks and a Marker of Environmental Stress and Disease Activity in Lupus

被引：0
|
作者：
Namas, Rajaie [1 ]
Renauer, Paul [1 ]
Ognenovski, Mikhail [1 ]
Tsou, Pei-Suen [1 ]
Sawalha, Amr H. [1 ]
机构：
[1] Univ Michigan, Div Rheumatol, Ann Arbor, MI 48109 USA
来源：
ARTHRITIS & RHEUMATOLOGY | 2015年 / 67卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
3080
引用
收藏
页数：1
相关论文
共 50 条
  • [21] DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner
    Patrick L. Collins
    Caitlin Purman
    Sofia I. Porter
    Vincent Nganga
    Ankita Saini
    Katharina E. Hayer
    Greer L. Gurewitz
    Barry P. Sleckman
    Jeffrey J. Bednarski
    Craig H. Bassing
    Eugene M. Oltz
    Nature Communications, 11
  • [22] DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner
    Collins, Patrick L.
    Purman, Caitlin
    Porter, Sofia, I
    Nganga, Vincent
    Saini, Ankita
    Hayer, Katharina E.
    Gurewitz, Greer L.
    Sleckman, Barry P.
    Bednarski, Jeffrey J.
    Bassing, Craig H.
    Oltz, Eugene M.
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [23] Does γH2AX foci formation depend on the presence of DNA double strand breaks?
    Takahashi, A
    Ohnishi, T
    CANCER LETTERS, 2005, 229 (02) : 171 - 179
  • [24] γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
    Kinner, Andrea
    Wu, Wenqi
    Staudt, Christian
    Iliakis, George
    NUCLEIC ACIDS RESEARCH, 2008, 36 (17) : 5678 - 5694
  • [25] Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability
    Yu, T.
    MacPhail, S. H.
    Banath, J. P.
    Klokov, D.
    Olive, P. L.
    DNA REPAIR, 2006, 5 (08) : 935 - 946
  • [26] Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks
    Banáth, JP
    Olive, PL
    CANCER RESEARCH, 2003, 63 (15) : 4347 - 4350
  • [27] Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks
    Svetlova, M. P.
    Solovjeva, L. V.
    Tomilin, N. V.
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2010, 685 (1-2) : 54 - 60
  • [28] Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response
    Wu, Ching-Yuan
    Kang, Hong-Yo
    Yang, Wei-Lei
    Wu, Juan
    Jeong, Yun Seong
    Wang, Jing
    Chan, Chia-Hsin
    Lee, Szu-Wei
    Zhang, Xian
    Lamothe, Betty
    Campos, Alejandro D.
    Darnay, Bryant G.
    Lin, Hui-Kuan
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (35) : 30806 - 30815
  • [29] DNA Double-Strand Breaks by Cr(VI) Are Targeted to Euchromatin and Cause ATR-Dependent Phosphorylation of Histone H2AX and Its Ubiquitination
    DeLoughery, Zachary
    Luczak, Michal W.
    Ortega-Atienza, Sara
    Zhitkovich, Anatoly
    TOXICOLOGICAL SCIENCES, 2015, 143 (01) : 54 - 63
  • [30] Double strand break repair functions of histone H2AX
    Scully, Ralph
    Xie, Anyong
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2013, 750 (1-2) : 5 - 14
12345