Prevalence of celiac disease markers in a French cohort of children and adolescents with type 1 diabetes mellitus

被引：3
|
作者：
Beltran, S [1 ]
Bony-Trifunovic, H
Gouilleux-Gruart, V
Djeddi, D
Dadamessi, I
Dupas, JL
Boudailliez, B
机构：
[1] Hop Nord Amiens, Unites Diabetol & Gastroenterol, Serv Pediat Med & Med Adolescent, F-80054 Amiens 1, France
[2] CHU Amiens, Immunol Lab, Amiens, France
[3] CHU Amiens, Serv Hepatogastroenterol, Amiens, France
来源：
ANNALES D ENDOCRINOLOGIE | 2004年 / 65卷 / 02期
关键词：
diabetes mellitus type 1; celiac disease; autoimmunity;
D O I：
10.1016/S0003-4266(04)95661-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The aim of this study was to determine the prevalence of celiac disease (CD) markers in a French cohort of 84 children type 1 diabetics. Detection of antitransglutaminase (AtTG), antiencomysium (AEA) and antigliadin (AGA) antibodies was performed. Group 1 included 81 (96.4%) diabetic patients with negative antibodies. Group 2 included 3 patients (3.6%) with positive serological markers: 1 AGA-AEA-AtTG and 1 AEA-AtTG with proved histological diagnosis and I AGA positive with negative histology. No statistically significant difference was observed between the groups with regard to age, duration of diabetes, familial target stature, and ratios Height/Age and Weight/Height. Presence of CD serological markers was related to a lower level of HbA1c. Prevalence of CD serological markers is important in this French cohort but lower than other countries.
引用
收藏
页码：131 / 135
页数：5
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