Preparation of porous hydroxyapatite particles to be used as drug delivery systems

被引：6
|
作者：
Martins, MA [1 ]
Santos, C [1 ]
Costa, MEV [1 ]
Almeida, MM [1 ]
机构：
[1] Univ Aveiro, CICECO, Dept Ceram & Glass Engn, P-3810193 Aveiro, Portugal
来源：
ADVANCED MATERIALS FORUM II | 2004年 / 455-456卷
关键词：
hydroxyapatite; nanoparticles; porous particles; drug delivery; bioceramics;
D O I：
10.4028/www.scientific.net/MSF.455-456.353
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Porous apatite particles with an average diameter of 3-4 mum were produced by spray drying a suspension of apatite nanoparticles, which were previously obtained by precipitation in a calcium/citrate/phosphate solution. The high surface area of the porous particles indicates a highly porous structure. The so produced spray dried apatite particles have the capability to adsorb and release a model drug compound (salicylic acid) in solutions at physiological pH.
引用
收藏
页码：353 / 357
页数：5
相关论文
共 50 条
  • [21] Porous hollow hydroxyapatite microspheres synthesized by spray pyrolysis using a microalga template: preparation, drug delivery, and bioactivity
    Sambudi, Nonni Soraya
    Cho, Sunja
    Cho, Kuk
    RSC ADVANCES, 2016, 6 (49): : 43041 - 43048
  • [22] Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles
    Shirosaki, Yuki
    Okamoto, Kohei
    Hayakawa, Satoshi
    Osaka, Akiyoshi
    Asano, Takuji
    BIOMED RESEARCH INTERNATIONAL, 2015, 2015
  • [23] Hydrothermal fabrication of porous hollow hydroxyapatite microspheres for a drug delivery system
    Lai, Wen
    Chen, Cen
    Ren, Xiaoyuan
    Lee, In-Seop
    Jiang, Guohua
    Kong, Xiangdong
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 62 : 166 - 172
  • [24] Hierarchical porous hydroxyapatite fibers with a hollow structure as drug delivery carriers
    Yi, Zhongchao
    Wang, Kai
    Tian, Jiarong
    Shu, Yue
    Yang, Jian
    Xiao, Wenqian
    Li, Bo
    Liao, Xiaoling
    CERAMICS INTERNATIONAL, 2016, 42 (16) : 19079 - 19085
  • [25] Preparation and characterization of biopolymeric nanoparticles used in drug delivery
    Ramachandran, Radhika
    Shanmughavel, Piramanayagam
    INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, 2010, 47 (01): : 56 - 59
  • [26] Preparation of doxorubicin loaded Poly(ethylene glycol)-Poly(?-caprolactone)-hydroxyapatite fibres as drug delivery systems
    Guo, Qingfa
    Kong, Fanyuan
    Ma, Chengliang
    Cao, Hui
    MATERIALS TECHNOLOGY, 2020, 35 (04) : 203 - 211
  • [27] DRUG DELIVERY SYSTEMS USED FOR BIOLOGICAL PRODUCTS
    Saka, Ongun Mehmet
    JOURNAL OF RESEARCH IN PHARMACY, 2023, 27 : 4 - 6
  • [28] Porous Inorganic Drug Delivery Systems—a Review
    E. Sayed
    R. Haj-Ahmad
    K. Ruparelia
    M. S. Arshad
    M.-W. Chang
    Z. Ahmad
    AAPS PharmSciTech, 2017, 18 : 1507 - 1525
  • [29] FORMATION OF POROUS MEMBRANES FOR DRUG DELIVERY SYSTEMS
    VANDEWITTE, P
    ESSELBRUGGE, H
    PETERS, AMP
    DIJKSTRA, PJ
    FEIJEN, J
    GROENEWEGEN, RJJ
    SMID, J
    OLIJSLAGER, J
    SCHAKENRAAD, JM
    EENINK, MJD
    SAM, AP
    JOURNAL OF CONTROLLED RELEASE, 1993, 24 (1-3) : 61 - 78
  • [30] DRUG PREPARATION TECHNIQUES FOR IV DRUG DELIVERY SYSTEMS
    COLANGELO, A
    AMERICAN JOURNAL OF HOSPITAL PHARMACY, 1987, 44 (11): : 2550 - 2553
12345