Structural Insights into the Central Complement Ccomponent C3

被引:0
|
作者
Gros, Piet [1 ]
Janssen, Bert J. C. [1 ]
Huizinga, Eric G. [1 ]
Raaijmakers, Hans C. A. [1 ]
Roos, Anja [2 ]
Daha, Moh R. [2 ]
机构
[1] Univ Utrecht, Dept Crystal & Struct Chem, Utrecht, Netherlands
[2] Leiden Univ, Dept Nephrol, Med Ctr, Leiden, Netherlands
关键词
immunology; complement; plasma proteins;
D O I
10.1107/S0108767305096121
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
MS71.29.5
引用
收藏
页码:C91 / C92
页数:2
相关论文
共 50 条
  • [42] Engineering of human complement component C3 for catalytic inhibition of complement
    Kölln, J
    Bredehorst, R
    Spillner, E
    IMMUNOLOGY LETTERS, 2005, 98 (01) : 49 - 56
  • [43] COMPLEMENT COMPONENTS OF C3 AND C4 IN NIGERIANS
    OLUSI, SO
    MCFARLANE, H
    TROPICAL AND GEOGRAPHICAL MEDICINE, 1975, 27 (03): : 262 - 264
  • [44] Structure-Function-Disease map for the genetic abnormalities in the central complement component C3
    Roumenina, L. T.
    Halbwachs-Mecarelli, L.
    Bordereau, P.
    Rybkine, T.
    Dragon-Durey, M. A.
    Noris, M.
    Sautes-Fridman, C.
    Fremeaux-Bacchi, V.
    MOLECULAR IMMUNOLOGY, 2011, 48 (14) : 1674 - 1674
  • [45] Complement C3 is downregulated following ranibizumab intervention in experimental central retinal vein occlusion
    Cehofski, Lasse Jorgensen
    Kruse, Anders
    Maeng, Mads Odgaard
    Kjaergaard, Benedict
    Sejergaard, Benn Falch
    Schlosser, Anders
    Sorensen, Grith Lykke
    Honore, Bent
    Vorum, Henrik
    MOLECULAR VISION, 2024, 30 : 268 - 277
  • [46] STRUCTURAL REQUIREMENTS FOR THIOESTER BOND FORMATION IN HUMAN-COMPLEMENT COMPONENT C3 - REASSESSMENT OF THE ROLE OF THIOESTER BOND INTEGRITY ON THE CONFORMATION OF C3
    ISAAC, L
    ISENMAN, DE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1992, 267 (14) : 10062 - 10069
  • [47] The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome
    Martinez-Barricarte, Ruben
    Heurich, Meike
    Lopez-Perrote, Andres
    Tortajada, Agustin
    Pinto, Sheila
    Lopez-Trascasa, Margarita
    Sanchez-Corral, Pilar
    Morgan, B. Paul
    Llorca, Oscar
    Harris, Claire L.
    Rodriguez de Cordoba, Santiago
    MOLECULAR IMMUNOLOGY, 2015, 66 (02) : 263 - 273
  • [48] Development of a complement C3 humanized rat as a new model for evaluating novel C3 inhibitors
    Lin, Feng
    Zhang, Lingjun
    Yang, Maojing
    Hughes, Elizabeth
    Saunders, Thomas
    Chen, Jin
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (08)
  • [49] New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3
    Rodriguez, Elizabeth
    Rallapalli, Pavithra M.
    Osborne, Amy J.
    Perkins, Stephen J.
    BIOSCIENCE REPORTS, 2014, 34 : 635 - 649
  • [50] Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor
    Rooijakkers, Suzan H. M.
    Wu, Jin
    Ruyken, Maartje
    van Domselaar, Robert
    Planken, Karel L.
    Tzekou, Apostolia
    Ricklin, Daniel
    Lambris, John D.
    Janssen, Bert J. C.
    van Strijp, Jos A. G.
    Gros, Piet
    NATURE IMMUNOLOGY, 2009, 10 (07) : 721 - U72