Evaluation of H3K27me3 Expression as a Marker of EZH2 Activation in SMARCA4/SMARCA2-Deficient Tumors and Candidate Biomarker for Trials of EZH2 Inhibitors

被引：0
|
作者：
Kezlarian, Brie [1 ]
Montecalvo, Joseph [2 ]
Sauter, Jennifer [1 ]
Travis, William [1 ]
Gounder, Mrinal [1 ]
Rudin, Charles [1 ]
Ladanyi, Marc [1 ]
Namakydoust, Azadeh [3 ]
Rekhtman, Natasha [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[2] Suny Downstate Med Ctr, New York, NY USA
[3] Mem Sloan Kettering Canc Ctr, Middletown, NJ USA
来源：
MODERN PATHOLOGY | 2019年 / 32卷
关键词：
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
1844
引用
收藏
页数：2
相关论文
共 50 条
  • [21] The epigenetic EZH2/H3K27me3 axis modulates lactotroph tumor cell proliferation
    Zlocowski, N.
    Sosa, L. d, V
    De la Cruz-Thea, B.
    Guido, C. B.
    Martin, M. G.
    Mukdsi, J. H.
    Torres, A., I
    Petiti, J. P.
    JOURNAL OF ENDOCRINOLOGY, 2023, 257 (02)
  • [22] H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade
    Hoffmann, Friederike
    Niebel, Dennis
    Aymans, Pia
    Ferring-Schmitt, Sandra
    Dietrich, Dimo
    Landsberg, Jennifer
    CLINICAL EPIGENETICS, 2020, 12 (01)
  • [23] H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade
    Hoffmann, F.
    Niebel, D.
    Aymans, P.
    Ferring-Schmitt, S.
    Dietrich, D.
    Landsberg, J.
    EXPERIMENTAL DERMATOLOGY, 2023, 32 (04) : E111 - E112
  • [24] H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade
    Friederike Hoffmann
    Dennis Niebel
    Pia Aymans
    Sandra Ferring-Schmitt
    Dimo Dietrich
    Jennifer Landsberg
    Clinical Epigenetics, 2020, 12
  • [25] Mutually exclusive expression of EZH2 and H3K27me3 in non-small cell lung carcinoma
    Onishi, Takafumi
    Takashima, Tsuyoshi
    Kurashige, Masako
    Ohshima, Kenji
    Morii, Eiichi
    PATHOLOGY RESEARCH AND PRACTICE, 2022, 238
  • [26] EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer
    Chinaranagari, Swathi
    Sharma, Pankaj
    Chaudhary, Jaideep
    ONCOTARGET, 2014, 5 (16) : 7172 - 7182
  • [27] Evaluation of H3K27me3 and EZH2 in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant GBM
    Venneti, Sriram
    Garimella, Mihir
    Sullivan, Lisa
    Martinez, Daniel
    Huse, Jason
    Heguy, Adriana
    Santi, Mariarita
    Thompson, Craig
    Thompson, Craig
    Alexander, Judkins
    CANCER RESEARCH, 2013, 73
  • [28] Evaluation of H3K27me3 and EZH2 in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 in H3F3A K27M Mutant GBM
    Venneti, Sriram
    Garimella, Mihir
    Sullivan, Lisa
    Martinez, Daniel
    Huse, Jason
    Heguy, Adriana
    Santi, Mariarita
    Thompson, Craig
    Judkins, Alexander
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2013, 72 (06): : 574 - 574
  • [29] EVALUATION OF H3K27ME3 AND EZH2 IN PEDIATRIC GLIAL AND GLIONEURONAL TUMORS SHOWS DECREASED H3K27me3 IN H3F3A K27M MUTANT GBM
    Venneti, Sriram
    Garimella, Mihir
    Sullivan, Lisa
    Martinez, Daniel
    Huse, Jason
    Heguy, Adriana
    Santi, Mariarita
    Thompson, Craig
    Judkins, Alexander
    NEURO-ONCOLOGY, 2013, 15 : 163 - 163
  • [30] EZH2 suppresses insulinoma development by epigenetically reducing KIF4A expression via H3K27me3 modification
    Zhang, Suzhen
    Liu, Jun
    Li, Feng
    Yang, Mudan
    Wang, Junping
    GENE, 2022, 822
12345