Prognosis and response to therapy in colorectal cancer

被引：43
|
作者：
Walker, J [1 ]
Quirke, P [1 ]
机构：
[1] Univ Leeds, Dept Pathol, Leeds LS2 9JT, W Yorkshire, England
来源：
EUROPEAN JOURNAL OF CANCER | 2002年 / 38卷 / 07期
关键词：
colorectal; surgery; tumour biology; circumferential resection; margin; histopathological staging;
D O I：
10.1016/S0959-8049(02)00044-8
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Colorectal cancer is Europe's second biggest cancer killer. Yet despite advances in knowledge and changes in chemotherapy practice, we have not seen great strides in improved survival. Histopathological staging is at present the most accurate prognostic factor for survival and recurrence. Improvements in staging have led to the recognition of the importance of the circumferential resection margin (CRM) and how the quality of surgery influences local recurrence rates. Further refinements in staging and increasing knowledge of tumour biology will have a large contribution to play in the future. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：880 / 886
页数：7
相关论文
共 50 条
  • [1] Determinants of prognosis and response to therapy in colorectal cancer
    Iqbal S.
    Lenz H.-J.
    [J]. Current Oncology Reports, 2001, 3 (2) : 102 - 108
  • [2] CYTOKERATINS IN PREDICTING THERAPY RESPONSE AND PROGNOSIS OF COLORECTAL CANCER PATIENTS
    Holdenrieder, S.
    Stieber, P.
    Liska, V.
    Treska, V.
    Topolcan, O.
    Finek, J.
    Holubec, L.
    [J]. CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2011, 49 : S244 - S244
  • [3] Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer
    Sebastian Foersch
    Christina Glasner
    Ann-Christin Woerl
    Markus Eckstein
    Daniel-Christoph Wagner
    Stefan Schulz
    Franziska Kellers
    Aurélie Fernandez
    Konstantina Tserea
    Michael Kloth
    Arndt Hartmann
    Achim Heintz
    Wilko Weichert
    Wilfried Roth
    Carol Geppert
    Jakob Nikolas Kather
    Moritz Jesinghaus
    [J]. Nature Medicine, 2023, 29 : 430 - 439
  • [4] Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer
    Foersch, Sebastian
    Glasner, Christina
    Woerl, Ann-Christin
    Eckstein, Markus
    Wagner, Daniel-Christoph
    Schulz, Stefan
    Kellers, Franziska
    Fernandez, Aurelie
    Tserea, Konstantina
    Kloth, Michael
    Hartmann, Arndt
    Heintz, Achim
    Weichert, Wilko
    Roth, Wilfried
    Geppert, Carol
    Kather, Jakob Nikolas
    Jesinghaus, Moritz
    [J]. NATURE MEDICINE, 2023, 29 (02) : 430 - 439
  • [5] Haemostatic biomarkers for prognosis and prediction of therapy response in patients with metastatic colorectal cancer
    Moik, Florian
    Posch, Florian
    Grilz, Ella
    Scheithauer, Werner
    Pabinger, Ingrid
    Prager, Gerald
    Ay, Cihan
    [J]. THROMBOSIS RESEARCH, 2020, 187 : 9 - 17
  • [6] Usefulness of BCRP in colorectal cancer prognosis and therapy
    Salagacka, A.
    Balcerczak, E.
    Mirowski, M.
    Pasz-Walczak, G.
    Malewski, T.
    [J]. FEBS JOURNAL, 2008, 275 : 69 - 69
  • [7] Coffee Consumption and Colorectal Cancer Prognosis RESPONSE
    Wang, Shunan
    Zhang, Zhixin
    Niu, Wenquan
    [J]. JAMA ONCOLOGY, 2021, 7 (05) : 778 - 778
  • [8] Unsupervised analyses reveal molecular subtypes associated to prognosis and response to therapy in colorectal cancer
    Sanz-Pamplona, Rebeca
    Santos, Cristina
    Grasselli, Julieta
    Mollevi, David G.
    Dienstmann, Rodrigo
    Pare-Brunet, Laia
    Sanjuan, Xavier
    Biondo, Sebastiano
    Capella, Gabriel
    Tabernero, Josep
    Salazar, Ramon
    Moreno, Victor
    [J]. COLORECTAL CANCER, 2014, 3 (03) : 277 - 288
  • [9] Alternative polyadenylation associated with prognosis and therapy in colorectal cancer
    Yi Zhang
    Yunfei Xu
    Yuzhi Wang
    [J]. Scientific Reports, 12
  • [10] Alternative polyadenylation associated with prognosis and therapy in colorectal cancer
    Zhang, Yi
    Xu, Yunfei
    Wang, Yuzhi
    [J]. SCIENTIFIC REPORTS, 2022, 12 (01)
12345