Synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction under catalyst-free conditions

被引：9
|
作者：
Chen, Yang [2 ]
Wang, Ren [3 ]
Ba, Feifei [2 ]
Hou, Junli [2 ]
Ding, Aishun [1 ]
Zhou, Mingdong [2 ]
Guo, Hao [1 ]
机构：
[1] Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China
[2] Liaoning Shihua Univ, Sch Chem & Mat Sci, Dandong Rd 1, Fushun 113001, Peoples R China
[3] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai Inst Ultrasound Med, Dept Ultrasound Med, Shanghai 200233, Peoples R China
来源：
JOURNAL OF SAUDI CHEMICAL SOCIETY | 2017年 / 21卷 / 01期
基金：
对外科技合作项目（国际科技项目）;
关键词：
Three-component domino reaction; Imidazole; Catalyst-free; Synthesis; Green chemistry; ONE-POT SYNTHESIS; 2,4,5-TRISUBSTITUTED IMIDAZOLES; MICROWAVE IRRADIATION; EFFICIENT; 2,4,5-TRIARYLIMIDAZOLES; DERIVATIVES; INHIBITORS;
D O I：
10.1016/j.jscs.2016.03.001
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-pot synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction of 2,2-dibromo-1,2-diarylethanones, ammonium acetate, and aryl aldehydes under catalyst-free conditions is developed. The scope of this reaction is studied. A possible mechanism is proposed based on experimental results. (C) 2016 King Saud University. Production and hosting by Elsevier B.V.
引用
收藏
页码：76 / 81
页数：6
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