Non-coding RNAs and ovarian diseases (Review)

被引：10

作者：

Li, Dandan ^{[1
]}

Xu, Duo ^{[2
]}

Zou, Yinggang ^{[1
]}

Xu, Ying ^{[1
]}

Fu, Lulu ^{[1
]}

Xu, Xin ^{[1
]}

Liu, Yongzheng ^{[1
]}

Zhang, Xueying ^{[1
]}

Zhang, Jingshun ^{[1
]}

Ming, Hao ^{[1
]}

Zheng, Lianwen ^{[1
]}

机构：

[1] Jilin Univ, Dept Obstet & Gynecol, Reprod Med Ctr, Hosp 2, 218 Ziqiang St, Changchun 130062, Jilin, Peoples R China

[2] Tumor Hosp Jilin Prov, Dept Breast Oncol, Changchun 130021, Jilin, Peoples R China

来源：

MOLECULAR MEDICINE REPORTS | 2017年 / 15卷 / 04期

关键词：

non-coding RNA; ovarian tumor; polycystic ovary syndrome; premature ovarian failure; diagnosis; DIFFERENTIALLY EXPRESSED MICRORNAS; SMALL INTERFERING RNAS; X-SPECIFIC TRANSCRIPT; SMALL NUCLEOLAR RNAS; HUMAN BREAST-CANCER; GENE-EXPRESSION; IN-VIVO; FOLLICULAR-FLUID; CELLS; GENOME;

D O I：

10.3892/mmr.2017.6176

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Non-coding RNAs (ncRNAs) are a diverse family of untranslated transcripts, which serve important roles in numerous biological processes. ncRNAs are emerging as major mediators of gene expression with crucial regulatory functions. Ovarian diseases have a wide variety of clinical pathological types, which have serious impacts on women's health. In this review, current studies on ncRNAs are summarized with respect to ovarian diseases. Understanding of the role of ncRNAs in ovarian diseases is currently limited; further studies on the molecular mechanisms by which abnormal expression of ncRNAs contributes to ovarian diseases will aid in the identification of ncRNAs as novel diagnostic markers and therapeutic targets for ovarian diseases.

引用

页码：1435 / 1440

页数：6

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