Prion diseases:: a dual view of the prion hypothesis as seen from a distance

被引:0
|
作者
Liberski, PP
Jaskólski, M
机构
[1] Med Acad Lodz, Dept Mol Biol, Lab Electron Microscop & Neuropathol, Chair Oncol, PL-92216 Lodz, Poland
[2] Polish Mother Mem Hosp, Dept Neurosurg, Lodz, Poland
[3] Adam Mickiewicz Univ, Fac Chem, Dept Crystallog, Poznan, Poland
[4] Polish Acad Sci, Inst Bioorgan Chem, Ctr Biocrystallog Res, Poznan, Poland
关键词
prion theory; structural biology;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We review the historical background and principles of the prion theory in its current shape. We showed that most of data may be still interpreted dually according to the protein only hypothesis and according to the theory in which additional component is necessary to comprise the infectivity. The enormous impact of structural biological studies is also stressed.
引用
收藏
页码:197 / 226
页数:30
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