Hypokalaemia and peripheral oedema in a Cushingoid patient with metastatic prostate cancer

被引：0
|
作者：
Schepers, L. M. [1 ]
Kisters, J. M. H. [1 ]
Wetzels, C. [2 ]
Creemers, G. J. [1 ]
机构：
[1] Catharina Hosp, Dept Internal Med, Eindhoven, Netherlands
[2] Jeroen Bosch Hosp, Dept Pathol, Shertogenbosch, Netherlands
来源：
NETHERLANDS JOURNAL OF MEDICINE | 2020年 / 78卷 / 06期
关键词：
Cushing's syndrome; ectopic ACTH production; large cell neuroendocrine carcinoma; prostate cancer; NEUROENDOCRINE DIFFERENTIATION;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report on a 75-year-old man with a history of metastatic prostate cancer who presented with haematuria, peripheral oedema, metabolic alkalosis, hypokalaemia, and hypertension. Laboratory evaluation was compatible with the diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome and suggestive of ectopic ACTH production. Pathology of a prostate biopsy specimen showed a large cell neuroendocrine carcinoma (LCNEC) of the prostate. This report describes a case of Cushing's syndrome that was probably caused by ectopic ACTH secretion by a LCNEC of the prostate.
引用
收藏
页码：401 / 403
页数：3
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