Let X be a completely regular Hausdorff space and let Ba stand for the Baire sigma-algebra of sets in X. For a Banach space E let C-rc(X, E) be the space of all continuous functions f : X -> E such that f (X) is a relatively compact set in E, and let B(Ba, E) be the space of all totally Ba-measurable functions f : X -> E. For a Banach space Y we study the problem of extension of some natural classes of bounded linear operators T : C-rc(X, E) -> Y to operators (T) over bar : B(Ba, E) -> Y. (C) 2015 Royal Dutch Mathematical Society (KWG). Published by Elsevier B.V. All rights reserved.