Fabrication and Characterization of PVCP Human Breast Tissue-mimicking Phantom for Photoacoustic Imaging

被引：16

作者：

Jeong, Eun-ju ^{[1
]}

Song, Hyun-Woo ^{[1
]}

Lee, Yong-Jae ^{[1
]}

Park, Su Jun ^{[1
]}

Yim, Mi Jung ^{[2
]}

Lee, Su Sung ^{[2
]}

Kim, Bong Kyu ^{[1
]}

机构：

[1] Elect & Telecommun Res Inst, Biomed IT Convergence Res Dept, Diagnost Device Res Sect, 218 Gajeong Ro, Daejeon 34129, South Korea

[2] Alpin Med Syst, Seoul 08393, South Korea

来源：

BIOCHIP JOURNAL | 2017年 / 11卷 / 01期

关键词：

Medical optics; Biotechnology; Photo acoustic imaging; Tissue-mimicking phantom; Polyvinyl chloride plastisol (PVCP); OPTICAL-PROPERTIES;

D O I：

10.1007/s13206-016-1109-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Human tissue-mimicking phantoms are important for characterizing and optimizing ultrasound and photoacoustic imaging systems. We demonstrated the applicability of a polyvinyl chloride plastisol (PVCP) phantom to photoacoustic imaging studies. The acoustic properties of the fabricated PVCP phantom were measured to have a sound speed of 1.370 m/s, attenuation coefficient of 0.71 dB/cm/MHz, and acoustic impedance of 1.39 Mrayl. Reduced scattering coefficients, absorption coefficient, and refractive index were obtained, as 1.31 mm(-1), 0.001 mm(-1), and 1.636 at 780 nm by optical measurements, respectively. Therefore, the PVCP phantom was found to be similar enough to human breast tissue in photoacoustic properties.

引用

页码：67 / 75

页数：9

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