Fabrication and Characterization of PVCP Human Breast Tissue-mimicking Phantom for Photoacoustic Imaging

被引:16
|
作者
Jeong, Eun-ju [1 ]
Song, Hyun-Woo [1 ]
Lee, Yong-Jae [1 ]
Park, Su Jun [1 ]
Yim, Mi Jung [2 ]
Lee, Su Sung [2 ]
Kim, Bong Kyu [1 ]
机构
[1] Elect & Telecommun Res Inst, Biomed IT Convergence Res Dept, Diagnost Device Res Sect, 218 Gajeong Ro, Daejeon 34129, South Korea
[2] Alpin Med Syst, Seoul 08393, South Korea
关键词
Medical optics; Biotechnology; Photo acoustic imaging; Tissue-mimicking phantom; Polyvinyl chloride plastisol (PVCP); OPTICAL-PROPERTIES;
D O I
10.1007/s13206-016-1109-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Human tissue-mimicking phantoms are important for characterizing and optimizing ultrasound and photoacoustic imaging systems. We demonstrated the applicability of a polyvinyl chloride plastisol (PVCP) phantom to photoacoustic imaging studies. The acoustic properties of the fabricated PVCP phantom were measured to have a sound speed of 1.370 m/s, attenuation coefficient of 0.71 dB/cm/MHz, and acoustic impedance of 1.39 Mrayl. Reduced scattering coefficients, absorption coefficient, and refractive index were obtained, as 1.31 mm(-1), 0.001 mm(-1), and 1.636 at 780 nm by optical measurements, respectively. Therefore, the PVCP phantom was found to be similar enough to human breast tissue in photoacoustic properties.
引用
收藏
页码:67 / 75
页数:9
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