Development of a scalable chromatography process to separate empty and full adeno-associated vector (AAV) particles

被引:0
|
作者
Dickerson, Ryan [1 ]
Bakhshayeshi, Meisam [1 ]
机构
[1] Biogen, Tech Dev Gene Therapy, Somerville, MA USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
38
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Process Development for the Production and Purification of Adeno-Associated Virus (AAV)2 Vector using Baculovirus-Insect Cell Culture System
    Nasimuzzaman, Md
    Villaveces, Sophia
    van der Loo, Johannes C. M.
    Alla, Sivani
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2022, (179):
  • [32] Adeno-associated viral capsid stability on anion exchange chromatography column and its impact on empty and full capsid separation
    Khanal, Ohnmar
    Kumar, Vijesh
    Jin, Mi
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2023, 31
  • [33] Metabolically biotinylated adeno-associated virus (AAV) types 1, 2, 3, 4 and 5 for scalable purification and vector retargeting
    Sasser, AK
    Arnold, GS
    Bartlett, JS
    MOLECULAR THERAPY, 2004, 9 : S37 - S37
  • [34] Separation of full and empty adeno-associated virus particles using a novel multi-modal anion exchange membrane
    Hao, Xiaolei
    Horax, Ronny
    Wickramasinghe, S. Ranil
    Qian, Xianghong
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2025, 1255
  • [35] Development of an adeno-associated viral (AAV) vector targeted to murine myocardium by in vivo selection of an AAV-2 peptide display library
    Mueller, Oliver J.
    Ying, Ying
    Goehringer, Caroline
    Trepel, Martin
    Katus, Hugo A.
    Kleinschmidt, Juergen A.
    CIRCULATION, 2007, 116 (16) : 64 - 64
  • [36] DEVELOPMENT OF ADENO-ASSOCIATED VIRAL (AAV) VECTOR MEDIATED ANTI-ANGIOGENIC SYSTEMIC CANCER GENE THERAPY
    Miyake, Koichi
    Wang, Yizhuo
    Chen, Xiao
    Miyake, Noriko
    Shimada, Takashi
    JOURNAL OF GENE MEDICINE, 2009, 11 (12): : 1168 - 1169
  • [37] MULTI-OMICS DATA INTEGRATION TO IMPROVE ADENO-ASSOCIATED VECTOR (AAV) MANUFACTURING
    Esse, R.
    Martin, S.
    Lin, H.
    Sergijenko, A.
    Zucchelli, E.
    Marginean, D.
    O'Grady, C.
    Tiburcio, M. Lopes
    Evie, I.
    Chowdhury, F.
    Appleby, J.
    Di Cerbo, V.
    CYTOTHERAPY, 2024, 26 (06) : S133 - S133
  • [38] Genotyping of AAV Plasmid Stocks: Quality Control in Adeno-Associated Virus Vector Production
    Schmitt, Markus
    Pawlita, Michael
    Kleinschmidt, Juergen
    JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY, 2010, 19 (04) : 204 - 212
  • [39] Adeno-associated virus vector (AAV) microdystrophin gene therapy for Duchenne muscular dystrophy
    Dickson, George
    Le Guiner, Caroline
    Servais, Laurent
    Montus, Marie
    Hogrel, Jean-Yves
    Cherel, Yan
    Carlier, Pierre
    Masurier, Carole
    Adjali, Oumeya
    Barnay-Toutain, Frederic
    Koo, Taeyoung
    Athanasopoulos, Takis
    Malerba, Alberto
    Le Heron, Anita
    Mavilio, Fulivi
    Moullier, Philippe
    Voit, Thomas
    HUMAN GENE THERAPY, 2014, 25 (11) : A27 - A27
  • [40] Improving adeno-associated vector (AAV) manufacturing bottleneck by unravelling HEK cell biology
    Esse, R.
    Martin, S.
    Lin, H. Y.
    Sergijenko, A.
    Zucchelli, E.
    Evie, I.
    Tiburcio, M. Lopes
    Chowdhury, F.
    O'Grady, C.
    Marginean, D.
    Appleby, J.
    Di Cerbo, V.
    HUMAN GENE THERAPY, 2024, 35 (3-4) : A79 - A80