Phosphorylation of HPr by HPr Kinase in Gluconobacter oxydans 621H

被引：2

作者：

Zhang, Ping ^{[1
]}

Ma, Yushu ^{[1
]}

Wang, Fengqing ^{[1
]}

Wei, Dongzhi ^{[1
]}

机构：

[1] E China Univ Sci & Technol, New World Inst Biotechnol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

来源：

PROTEIN AND PEPTIDE LETTERS | 2014年 / 21卷 / 06期

关键词：

Gluconobacter oxydans; HPr; HPr kinase; phosphorylation; DEPENDENT PHOSPHOTRANSFERASE SYSTEM; GRAM-POSITIVE BACTERIA; CATABOLITE REPRESSION; ESCHERICHIA-COLI; PROTEIN-KINASE; ENZYME; COMPLEX; OPERON; EXPRESSION; SEQUENCE;

D O I：

10.2174/0929866521666140212111059

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

DNA sequencing has revealed that Gluconobacter oxydans may contain an incomplete phosphoenolpyruvate: carbohydrate phosphotransferase system (PTS), but the function of individual members of the system remains unknown. Here we demonstrated that the predicted histidine protein HPr, an essential component of PTS, can be phosphorylated by a predicted HPr kinase in G. oxydans, where Ser54 in HPr is the site responsible for such a phosphorylation. The discovery implies that G. oxydans may regulate PTS activity in a way similar to that identified in some Gram-positive bacteria with low GC content.

引用

页码：597 / 601

页数：5

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