Comorbidities as risk factors of chronic kidney disease in HIV-infected persons

被引：0
|
作者：
Marchewka, Zofia [1 ]
Szymczak, Aleksandra [2 ]
Knysz, Brygida [2 ]
机构：
[1] Uniwersytetu Med Piastow Slaskich Wroclawiu, Katedra & Zaklad Toksykol, Pracownia Markerow Nefrotoksycznosci Srodowiskowe, PL-51149 Wroclaw, Poland
[2] Uniwersytetu Med Piastow Slaskich Wroclawiu, Katedra & Klin Chorob Zakaznych Chorob Watroby &, Ul Koszarowa 5, PL-51149 Wroclaw, Poland
来源：
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ | 2015年 / 69卷
关键词：
chronic kidney disease; HIV; diabetes mellitus; arterial hypertension; hyperlipidemia; MULTICENTER AIDS COHORT; ANTIRETROVIRAL THERAPY; DIABETES-MELLITUS; BLOOD-PRESSURE; HIV-1-INFECTED PATIENTS; INSULIN-RESISTANCE; METABOLIC SYNDROME; RENAL DYSFUNCTION; TREATMENT-NAIVE; HYPERTENSION;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Significant survival prolongation in HIV-infected patients due to effective antiretroviral therapy is connected with increasing prevalence of chronic non-infective diseases in this population, among them chronic kidney disease. The pathogenesis of kidney disease in the setting of HIV includes conditions specific for HIV infection: direct effect of the virus, stage of immunodeficiency and drug toxicity. Chronic comorbidities, such as diabetes mellitus, hypertension, and hyperlipidemia, are additional significant risk factors of kidney disease. In HIV-infected individuals some distinct features of these conditions are observed, which are partly related to the virus and antiretroviral therapy. The article summarizes the effect of comorbidities on kidney function in HIV-infected persons.
引用
收藏
页码：1364 / 1370
页数：7
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