Acute Kidney Injury Before and After Liver Transplant

被引:16
|
作者
DellaVolpe, Jeffrey [1 ]
Al-Khafaji, Ali [2 ]
机构
[1] Methodist Healthcare Syst San Antonio, San Antonio, TX USA
[2] Univ Pittsburgh, Sch Med, Dept Crit Care Med, CRISMA Clin Res Invest & Syst Modeling Acute Illn, Pittsburgh, PA USA
关键词
acute kidney injury; oliguria; urine output; cirrhosis; renal failure; intensive care unit; mortality; GELATINASE-ASSOCIATED LIPOCALIN; ACUTE-RENAL-FAILURE; CRITICALLY-ILL PATIENTS; TYPE-1; HEPATORENAL-SYNDROME; CIRRHOTIC-PATIENTS; RIFLE CRITERIA; LIVING DONOR; RISK-FACTORS; INTRAVENOUS ALBUMIN; REPLACEMENT THERAPY;
D O I
10.1177/0885066618790558
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The development of acute kidney injury in the setting of liver disease is a significant event both before and after liver transplant. Whether acute kidney injury is the cause of or merely associated with worse outcomes, the development of renal failure is significant from a prognostic as well as from a diagnostic and therapeutic standpoint. Although not every etiology is reversible, there are number of etiologies that are correctable, to include hypovolemia, nephrotoxic medications, and acute tubular necrosis. In the post-liver transplant period, renal failure is associated with graft failure as well as worse outcomes overall. Prompt recognition, workup, and intervention can significantly impact outcomes and survival both before and after liver transplant.
引用
收藏
页码:687 / 695
页数:9
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