A Study on the Synthesis, Antimicrobial Activity, and Rapd Analysis of 3-phenyl-1,5-bis(4-(trifluoromethyl)phenyl)-1H-pyrazole

被引：0
|
作者：
Cetin, Adnan [1 ]
Bozari, Sedat [2 ]
机构：
[1] Mus Alparslan Univ, Dept Sci, Mus, Turkey
[2] Mus Alparslan Univ, Dept Mol Biol & Genet, Mus, Turkey
来源：
JOURNAL OF BIOCHEMICAL TECHNOLOGY | 2020年 / 11卷 / 03期
关键词：
Antibacterial; Amaranthus retroflexus; Germination experiment; Hordeum vulgare; PCR; Plant; BIOLOGICAL EVALUATION; FOOD SECURITY; CHALCONES; ANTICANCER; PESTICIDES;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
3-phenyl-1,5-bis(4-(trifluoromethyl)phenyl)-1H-pyrazole was synthesized and its structure was characterized by IR, NMR, and Elemental Analysis. The antimicrobial effects of pyrazole were investigated against seven bacteria (Bacillus subtilis ATCC 6633, Staphylococcus aureus 6538, Bacillus megaterium DSM 32 as gram-positive bacteria and Enterobacter aerogenes ATCC 13048, Pseudomonas aeruginosa 9027, Klebsiella pneumoniae RSKK 574 and Escherichia coli ATCC 25922) and three fungi organisms (Candida albicans ATCC 10231, Yarrovia lipolytica and Saccharomyces cerevisiae). Furthermore, the genomic stability values of designed pyrazole were observed in Hordeum vulgare and Amaranthus retroflexus L. from seeds based on random amplified-polymorphic DNA (RAPD) patterns compared to the five primers.
引用
收藏
页码：77 / 83
页数：7
相关论文
共 50 条
  • [1] Synthesis and Antimicrobial Studies of New Bis[4,5-dihydro-1-phenyl-5-thienyl-3-(phenyl-4-alkoxy)-1H-pyrazole] Derivatives
    Yusuf, Mohamad
    Jain, Payal
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (04) : 1162 - 1170
  • [2] 3,4-Dinitro-2,5-bis[4-(trifluoromethyl)phenyl]thiophene
    Huang, Ping-Hsin
    Shen, Jiun-Yi
    Wen, Yuh-Sheng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : 01469 - U1570
  • [3] Synthesis and characterization of novel fluorinated polyimides derived from bis[4-(4′-aminophenoxy)phenyl]-3,5-bis(trifluoromethyl)phenyl phosphine oxide
    Zhu, Yuanqin
    Zhao, Pinqiao
    Cai, Xuediao
    Meng, Wei-Dong
    Qing, Feng-Ling
    POLYMER, 2007, 48 (11) : 3116 - 3124
  • [4] SYNTHESIS OF NOVEL 3-(3,5-BIS (BENZYLOXY) PHENYL)-1-PHENYL-5-ARYL-4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITY STUDIES
    Subhashini, N. J. P.
    Chinthala, Sravanthi
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 25 (02) : 109 - 112
  • [5] 1,5-Bis(4-chlorophenyl)-3-[4-(dimethylamino)phenyl]pentane-1,5-dione
    Lei, Xinyou
    Bai, Xiaohua
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O514 - U1739
  • [6] STRUCTURE OF 1,5-BIS([4-(PENTYLOXY)PHENYL]AMINO)-9,10-ANTHRACENEDIONE
    FOITZIK, JK
    PAULUS, H
    HAASE, W
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1986, 42 : 108 - 109
  • [7] 3,5-Bis(4-bromophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole
    Samshuddin, S.
    Narayana, B.
    Yathirajan, H. S.
    Safwan, A. P.
    Tiekink, Edward R. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1279 - U299
  • [8] 1,1′,1"-{[4-(3,4-Ethylenedioxythiophen-2-yl)phenyl]methanetriyl}tris(1H-pyrazole)
    Chen, Xiao-Yan
    Yang, Xiaoping
    Holliday, Bradley J.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3021 - U1275
  • [9] 3,5-Bis(4-methoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole
    Baktir, Zeliha
    Akkurt, Mehmet
    Samshuddin, S.
    Narayana, B.
    Yathirajan, H. S.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O328 - U295
  • [10] 3,5-Bis(4-fluorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole
    Jasinski, Jerry P.
    Guild, Curtis J.
    Samshuddin, S.
    Narayana, B.
    Yathirajan, H. S.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1948 - U607
12345