Distance-based functional criticality in the human brain: intelligence and emotional intelligence

Background Anatomical distance has been identified as a key factor in the organizational principles of the human brain. On the other hand, criticality was proposed to accommodate the multiscale properties of human brain dynamics, and functional criticality based on resting-state functional magnetic resonance imaging (rfMRI) is a sensitive neuroimaging marker for human brain dynamics. Hence, to explore the effects of anatomical distance of the human brain on behaviors in terms of functional criticality, we proposed a revised algorithm of functional criticality called the distance-based vertex-wise index of functional criticality, and assessed this algorithm compared with the original neighborhood-based functional criticality. Results We recruited two groups of healthy participants, including young adults and middle-aged participants, for a total of 60 datasets including rfMRI and intelligence as well as emotional intelligence to study how human brain functional criticalities at different spatial scales contribute to individual behaviors. Furthermore, we defined the average distance between the particular behavioral map and vertices with significant functional connectivity as connectivity distance. Our results demonstrated that intelligence and emotional intelligence mapped to different brain regions at different ages. Additionally, intelligence was related to a wider distance range compared to emotional intelligence. Conclusions For different age groups, our findings not only provided a linkage between intelligence/emotional intelligence and functional criticality but also quantitatively characterized individual behaviors in terms of anatomical distance.